2-18-17 Flashcards

1
Q

it’s not birth, marriage, or death, but _______ which is truly the most important moment of your life

A

gastrulation

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2
Q

skin and nervous - formed during gastrulation

A

ectoderm

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3
Q

respiratory and digestive - formed in gastrulation

A

endoderm

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4
Q

connective tisseu, blood, heart - formed during gastrulation

A

mesoderm

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5
Q

week one embryonic development events

A

fertilization, morula, blastocycst, implantation

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6
Q

polyspermy-

A

multiple sperm

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7
Q

zona pellucida

A

translucent layer around Oocyte, sperm attachment site, protects zygote, implantation to the uterus

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8
Q

Oocyte

A

egg+sperm??

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9
Q

acrosomal vesicle was originally derived from______

A

golgi

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10
Q

how does one sperm recognize an Oocyte

A

specific receptor on head of sperm that recognize zona pellicula

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11
Q

how is polyspermy prevented

A

binding increases opening of sodium channels and release of cortical granules

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12
Q

activation of sperm

A

exocytosis of the acrosomal vesicle (containing proteases)

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13
Q

4 key steps of fertilization

A
  1. binding of sperm 2. acrosomal reaction 3. penetration through zona pellucida 4. fusion of plasma membranes 5 sperm nucleaus enters egg cytoplasm.
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14
Q

cleavage begins about ______ hours post fertilization

A

30

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15
Q

blastomeres are ________

A

totipotent

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16
Q

cleavage leads to _______of the ________

A

compaction , morula

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17
Q

the morula is tightly adhered within the ________ __________

A

zona pellucida

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18
Q

blastomere is _____ the blastula

A

before

19
Q

how many cells in a blastomere?

A

1

20
Q

totipotency synonym

A

multipotency

21
Q

the first cell differentiation event takes place in the __________

A

blastocyst

22
Q

parts of a blastocyst

A

blastocoel, zona pellucida, inner cell mass, trophoblast

23
Q

what portion of the blastocyst forms the embryo?

A

the inner cell mass

24
Q

Oct4 protein is expressed in the _______ cells of the __________

A

pluripotent ICM

25
Q

totipotent

A

can give rise to any other cell in the body

26
Q

pluripotent

A

can give rise to more than one other cell in the body

27
Q

you can make a cell pluripotent by the introduction of _____ _________

A

transcription factors

28
Q

we all _____ as embryos

A

hatch

29
Q

we hatch from the _____ ______

A

zona pellucida

30
Q

the chorion enables_______

A

the fetus to get oxegen and nutrients from the mother

31
Q

syntrhophoblast

A

multiple nuclei and ……

32
Q

3 types of monozygotic twins

A

unique chorion, shared chorion- ok, shared chorion-possible conjoined

33
Q

cyncytiotrophoblast

A

intermediary trophoblast with finger like projections

34
Q

ICM’s form originally into a _____ _______

A

bilaminar disc

35
Q

epiblast

A

part of the bilaminar disc

36
Q

hypoblast cells

A

part of the bilaminar disc

37
Q

connecting stalk connects to the _______

A

umbilical cord

38
Q

the hypoblast is pushed away to form the ______

A

endoderm

39
Q

top down order of first layers

A

ecto, meso, endoderm

40
Q

almost 2/3 of fertilized embyos ______

A

terminate

41
Q

how do you go from a sheet of cells into something as complex as a brain?

A

shaping, folding, closure

42
Q

MHP

A

medial hinge points

43
Q

folic acid supplements can prevent what?

A

50% of neural closure defects