1ST BIMEX Flashcards
TRUE of the Null cells EXCEPT:
humorally mediated immune response.
possess FC receptors
nonspecific cytotoxicity against virus-infected and tumor cells.
no cell surface determinants
humorally mediated immune response.
These cells lack nuclei & organelles:
platelets erythrocytes lymphocytes monocytes 1st & 2nd choices only 3rd & 4th choices only All of the above
erythrocytes
The strong basophilia of the granules in Basophils is due to the presence of the
following EXCEPT:
major basic proteins (MBP)
heparin
sulfated glycosaminoglycans (GAGs)
major basic proteins (MBP)
Both basophils and mast cells have surface receptors for what type of
immunoglobulin?
IgA IgM IgE SIG IgG Other:
IgE
This/These cells have metachromatic granules containing heparin and histamine.
basophils eosinophils neutrophils mast cells 1st & fourth cells only all the cells above
1st & fourth cells only
In larger blood vessels RBCs may adhere to one another loosely in stacks called
rouleaux formation
agglutination
coin formation
rolex formation
rouleaux formation
Identify the hemopoietic growth factors that activate and promote hemopoiesis
macrophage colony-stimulating factor
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
E. acts on monocyte progenitor cells
Identify the hemopoietic growth factors that activate and promote hemopoiesis
erythropoietin
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
F. acts on BFU-E and CFU-E
Identify the hemopoietic growth factors that activate and promote hemopoiesis
interleukin-3
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
B. acts on PHSC, CFU-S, & myeloid progenitor cells
Identify the hemopoietic growth factors that activate and promote hemopoiesis
interleukin-7
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
C. acts on CFU-Ly
Identify the hemopoietic growth factors that activate and promote hemopoiesis
granulocyte colony-stimulating factor
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
A. acts on granulocyte progenitor cells
Identify the hemopoietic growth factors that activate and promote hemopoiesis
granulocyte-macrophage colony-stimulating factor
A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E
D. acts on granulocyte and monocyte progenitor cells
This statement DON’T refer to the roles of Mitochondrial fusion & binary fission
A. Fusion counteracts the accumulation of mitochondrial mutations during aging
B. Fission serves to eliminate damaged organelles in order to allow their removal by autophagy
C. Fusion occurs under conditions of low cellular energy demand
D. Fission functions in partitioning and inheritance of the organelles during cell division
C. Fusion occurs under conditions of low cellular energy demand
This lymphocyte is responsible for the cellularly mediated immune response:
B cells
T cells
Null cells
T cells
Compare Animal & Plant Cells. (you may choose more than one answer)
cell membrane
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
endoplasmic reticulum
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
lysosomes
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
mitochondria
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
chloroplasts
A. animal cell
B. plant cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
nucelolus
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
nucleus usually at center
A. animal cell
B. plant cell
A. animal cell
Compare Animal & Plant Cells. (you may choose more than one answer)
nucleus
A. animal cell
B. plant cell
A. animal cell
B. plant cell
Compare Animal & Plant Cells. (you may choose more than one answer)
cell wall
A. animal cell
B. plant cell
B. plant cell
This leukocytes also remove antigen-antibody complexes from interstitial fluid by phagocytosis.
Basophils Neutrophils Monocytes Lymphocytes Eosinophils
Eosinophils
The cells actually responsible for storing fat in the marrow are the ________.
osteocytes
fibroblasts cells
adventitial reticular cells.
adipose cells
adipose cells
These leukocytes are abundant in the intestinal lining:
Monocytes Eosinophils Lymphocytes B & C only All
Eosinophils
AT what stage of the granulocytic series can each type be FRIST distinguished from each other?
mature granulocyte juvenile form myelocytes metamyelocytes myeloblast promyelocytes
myelocytes
The following refer to the granules of the Neutrophils EXCEPT:
A. Large azurophilic primary granules containing myeloperoxidase, lysozyme,
B. Smaller specific secondary granules containing collagenases, and bactericidal proteins
C. Tertiary granules contain gelatinase, cathepsins, and defensins
Tertiary granules contain gelatinase, cathepsins, and defensins
The prometer DNA in these cells is mostly unmethylated:
blood cells
muscle cells
sex cells
blood cells
Circulating platelets have a life span of about _____.
10days
1week
2weeks
20days
10days
The most abundant leukocyte
neutrophil basophil monocyte lymphocyte eosinophil
neutrophil
The following statements refer to human erythrocytes suspended in an isotonic
medium, EXCEPT:
2.6-µm thick at the rim,
flexible biconvex discs.
only 0.75-µm thick in the center.
approximately 7.5 µm in diameter,
flexible biconvex discs.
This is NOT among the functions of Smooth endoplasmic reticulum
A. detoxification of certain drugs and toxins such as barbiturates and alcohol
B. synthesis of cholesterols and lipids
C. regulate the production of integral membrane proteins
D. sequester and release calcium ions during skeletal muscle contraction and relaxation
C. regulate the production of integral membrane proteins
This is NOT CORRECT regarding platelets:
they are generally discoid
often appear in clumps
have lightly stained peripheral granulomere
sparse glycocalyx surrounding plasmalemma
have lightly stained peripheral granulomere
GRANULOMER IS CENTRAL ZONE
Normal concentration of erythrocytes in women:
150,000-450,000 /mm3
- 1-6.0 million/µL or mm3
- 9-5.5 million/µL or mm3
3.9-5.5 million/µL or mm3
This is the largest cell in the blood.
Eosinophils Neutrophils Lymphocytes Monocytes Basophils
Monocytes
This statement is TRUE regarding blood and bone marrow staining:
A. Cytoplasm takes up the acidic Eosin stain, while the nucleus is stained with basic Methylene blue.
B. Cytoplasm takes up the basic Eosin stain, while the nucleus is stained with acidic Methylene blue.
C. Cytoplasm & nucleus take up the acidic Eosin stain, while the interstitial background is stained with basic Methylene blue.
D. Cytoplasm takes up the basic Methylene blue stain, while the nucleus is stained with acidic
Eosin
A. Cytoplasm takes up the acidic Eosin stain, while the nucleus is stained with basic Methylene blue.
State the conditions during which the Mitochondria decides to undergo
Fission or Fusion
high energy demand
Fusion
State the conditions during which the Mitochondria decides to undergo
Fission or Fusion
cell division
Fission
State the conditions during which the Mitochondria decides to undergo
Fission or Fusion
counteracts mutations during aging -
Fusion
State the conditions during which the Mitochondria decides to undergo
Fission or Fusion
elimination of damaged organelles
Fission
State the conditions during which the Mitochondria decides to undergo
Fission or Fusion
apoptosis
Fission
They recognize epitopes (antigenic determinants) that are displayed by cells possessing HLA (human leukocyte antigen:
Null cells
B lymphocytes
Natural T killer cells
T lymphocytes
T lymphocytes
The following are Linege specific Hematopoietic Growth Factors EXCEPT:
IL-6 IL-5 Erythropoietin Thrombopoietin M-CSF G-CSF
IL-6
Trace the Red Cell development by assigning letters to the following cells by order of appearance:
Polychromato-philic erythroblasts pro-erythroblasts basophilic erythroblasts erythrocytes reticulocytes Ortho-chromatophilic erythroblasts
pro-erythroblasts - A basophilic erythroblasts - B Polychromato-philic erythroblasts - C Ortho-chromatophilic erythroblasts-D reticulocytes-E erythrocytes-F
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
cell membrane
both
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
membrane-bound nucleus
euk
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
multicelular organisms
euk
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
chromatin material
both
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
membrane bound organelles
euk
Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)
unicellular organisms
both
The leukocyte with the longest lifetime
lymphocyte eosinophil monocyte basophil neutrophil
lymphocyte
/???monocyte
These cells DO NOT arise from Monocytes as their precursor:
mast cells
osteoclasts
microglia
macrophages
mast cells
Which of the following contents of the Neutrophilic granules can degrade the components of bacterial cell walls?
gelatinase defensins collagenase cathepsins myeloperoxidase lysozyme
lysozyme
Senescent or worn out RBCs displaying swelling or other shape abnormalities are recognized and removed from circulation, mainly by macrophages of the following organs:
liver 2nd, 4th, & 5th choices only 1st, 2nd & 3rd choices only All of the above spleen bone marrow 1st, 2nd, & 5th choices only lymph node adrenals
1st, 2nd & 3rd choices only
LIVER, SPLEEN, BONE MARROW
Functions of Interleukins
interleukin-3
acts on PHSC, CFU-S, & myeloid progenitor cells
acts on CFU-Ly
acts on PHSC, CFU-S, & myeloid progenitor cells
Functions of Interleukins
interleukin-7
acts on PHSC, CFU-S, & myeloid progenitor cells
acts on CFU-Ly
acts on CFU-Ly
Synthesis of Proteins involves the following steps:
DNA REPLICATION TRANSCRIPTION TRANSLATION first 2 only last 2 only
last 2 only
This cell could divide more rapidly, producing large numbers of differentiated cells:
mature cells
stem cells
committed progenitor cells
committed progenitor cells
Which contents of the Eosinophils act to kill parasitic worms or helminths?
major basic proteins eosinophilic peroxidase arginine-rich factor 1st 2 choices only all of the above Other:
1st 2 choices only
Plasma contains proteins in the following decreasing order of quantity:
Regulatory Proteins-Globulin-Albumin-Fibrinogen
Globulin–Fibrinogen-Regulatory Proteins-Albumin
Albumin-Globulin-Fibrinogen-Regulatory Proteins
Globulin-Albumin-Fibrinogen-Regulatory Proteins
Albumin-Globulin-Fibrinogen-Regulatory Proteins
Give the roles of the following parts in the cell:
Inclusions
A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide
A. storage forms of nutrients, crystals, & pigments
Give the roles of the following parts in the cell:
Peroxisomes
A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide
C. contain catalase to break down hydrogen peroxide
Give the roles of the following parts in the cell:
Proteasomes
A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
This CORRECTLY states regarding each Golgi apparatus (complex):
A. It has a convex entry face, known as the cis face closer to the rough endoplasmic reticulum
B. Its exit face is concave, known as the medial face oriented toward the cell membrane
C. Between the entrance and the exit faces are intermediate cisternae, known as the trans face
D. It is composed of a cluster of vesicles, tubules, and flattened membrane-bounded cisternae
D. It is composed of a cluster of vesicles, tubules, and flattened membrane-bounded cisternae
The delta granules of platelets contain the following EXCEPT:
ATP
platelet derived growth factor
ADP
serotonin
platelet derived growth factor
