1ST BIMEX Flashcards

1
Q

TRUE of the Null cells EXCEPT:

humorally mediated immune response.
possess FC receptors
nonspecific cytotoxicity against virus-infected and tumor cells.
no cell surface determinants

A

humorally mediated immune response.

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2
Q

These cells lack nuclei & organelles:

platelets
erythrocytes
lymphocytes
monocytes
1st & 2nd choices only
3rd & 4th choices only
All of the above
A

erythrocytes

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3
Q

The strong basophilia of the granules in Basophils is due to the presence of the
following EXCEPT:

major basic proteins (MBP)
heparin
sulfated glycosaminoglycans (GAGs)

A

major basic proteins (MBP)

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4
Q

Both basophils and mast cells have surface receptors for what type of
immunoglobulin?

IgA
IgM
IgE
SIG
IgG
Other:
A

IgE

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5
Q

This/These cells have metachromatic granules containing heparin and histamine.

basophils
eosinophils
neutrophils
mast cells
1st & fourth cells only
all the cells above
A

1st & fourth cells only

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6
Q

In larger blood vessels RBCs may adhere to one another loosely in stacks called

rouleaux formation
agglutination
coin formation
rolex formation

A

rouleaux formation

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7
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

macrophage colony-stimulating factor

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

E. acts on monocyte progenitor cells

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8
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

erythropoietin

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

F. acts on BFU-E and CFU-E

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9
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

interleukin-3

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

B. acts on PHSC, CFU-S, & myeloid progenitor cells

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10
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

interleukin-7

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

C. acts on CFU-Ly

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11
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

granulocyte colony-stimulating factor

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

A. acts on granulocyte progenitor cells

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12
Q

Identify the hemopoietic growth factors that activate and promote hemopoiesis

granulocyte-macrophage colony-stimulating factor

A. acts on granulocyte progenitor cells
B. acts on PHSC, CFU-S, & myeloid progenitor cells
C. acts on CFU-Ly
D. acts on granulocyte and monocyte progenitor cells
E. acts on monocyte progenitor cells
F. acts on BFU-E and CFU-E

A

D. acts on granulocyte and monocyte progenitor cells

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13
Q

This statement DON’T refer to the roles of Mitochondrial fusion & binary fission

A. Fusion counteracts the accumulation of mitochondrial mutations during aging
B. Fission serves to eliminate damaged organelles in order to allow their removal by autophagy
C. Fusion occurs under conditions of low cellular energy demand
D. Fission functions in partitioning and inheritance of the organelles during cell division

A

C. Fusion occurs under conditions of low cellular energy demand

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14
Q

This lymphocyte is responsible for the cellularly mediated immune response:

B cells
T cells
Null cells

A

T cells

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15
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

cell membrane

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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16
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

endoplasmic reticulum

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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17
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

lysosomes

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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18
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

mitochondria

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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19
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

chloroplasts

A. animal cell
B. plant cell

A

B. plant cell

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20
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

nucelolus

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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21
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

nucleus usually at center

A. animal cell
B. plant cell

A

A. animal cell

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22
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

nucleus

A. animal cell
B. plant cell

A

A. animal cell

B. plant cell

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23
Q

Compare Animal & Plant Cells. (you may choose more than one answer)

cell wall

A. animal cell
B. plant cell

A

B. plant cell

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24
Q

This leukocytes also remove antigen-antibody complexes from interstitial fluid by phagocytosis.

Basophils
Neutrophils
Monocytes
Lymphocytes
Eosinophils
A

Eosinophils

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25
Q

The cells actually responsible for storing fat in the marrow are the ________.

osteocytes
fibroblasts cells
adventitial reticular cells.
adipose cells

A

adipose cells

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26
Q

These leukocytes are abundant in the intestinal lining:

Monocytes
Eosinophils
Lymphocytes
B & C only
All
A

Eosinophils

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27
Q

AT what stage of the granulocytic series can each type be FRIST distinguished from each other?

mature granulocyte
juvenile form
myelocytes
metamyelocytes
myeloblast
promyelocytes
A

myelocytes

28
Q

The following refer to the granules of the Neutrophils EXCEPT:

A. Large azurophilic primary granules containing myeloperoxidase, lysozyme,
B. Smaller specific secondary granules containing collagenases, and bactericidal proteins
C. Tertiary granules contain gelatinase, cathepsins, and defensins

A

Tertiary granules contain gelatinase, cathepsins, and defensins

29
Q

The prometer DNA in these cells is mostly unmethylated:

blood cells
muscle cells
sex cells

A

blood cells

30
Q

Circulating platelets have a life span of about _____.

10days
1week
2weeks
20days

A

10days

31
Q

The most abundant leukocyte

neutrophil
basophil
monocyte
lymphocyte
eosinophil
A

neutrophil

32
Q

The following statements refer to human erythrocytes suspended in an isotonic
medium, EXCEPT:

2.6-µm thick at the rim,
flexible biconvex discs.
only 0.75-µm thick in the center.
approximately 7.5 µm in diameter,

A

flexible biconvex discs.

33
Q

This is NOT among the functions of Smooth endoplasmic reticulum

A. detoxification of certain drugs and toxins such as barbiturates and alcohol
B. synthesis of cholesterols and lipids
C. regulate the production of integral membrane proteins
D. sequester and release calcium ions during skeletal muscle contraction and relaxation

A

C. regulate the production of integral membrane proteins

34
Q

This is NOT CORRECT regarding platelets:

they are generally discoid
often appear in clumps
have lightly stained peripheral granulomere
sparse glycocalyx surrounding plasmalemma

A

have lightly stained peripheral granulomere

GRANULOMER IS CENTRAL ZONE

35
Q

Normal concentration of erythrocytes in women:

150,000-450,000 /mm3

  1. 1-6.0 million/µL or mm3
  2. 9-5.5 million/µL or mm3
A

3.9-5.5 million/µL or mm3

36
Q

This is the largest cell in the blood.

Eosinophils
Neutrophils
Lymphocytes
Monocytes
Basophils
A

Monocytes

37
Q

This statement is TRUE regarding blood and bone marrow staining:

A. Cytoplasm takes up the acidic Eosin stain, while the nucleus is stained with basic Methylene blue.
B. Cytoplasm takes up the basic Eosin stain, while the nucleus is stained with acidic Methylene blue.
C. Cytoplasm & nucleus take up the acidic Eosin stain, while the interstitial background is stained with basic Methylene blue.
D. Cytoplasm takes up the basic Methylene blue stain, while the nucleus is stained with acidic
Eosin

A

A. Cytoplasm takes up the acidic Eosin stain, while the nucleus is stained with basic Methylene blue.

38
Q

State the conditions during which the Mitochondria decides to undergo

Fission or Fusion

high energy demand

A

Fusion

39
Q

State the conditions during which the Mitochondria decides to undergo

Fission or Fusion

cell division

A

Fission

40
Q

State the conditions during which the Mitochondria decides to undergo

Fission or Fusion

counteracts mutations during aging -

A

Fusion

41
Q

State the conditions during which the Mitochondria decides to undergo

Fission or Fusion

elimination of damaged organelles

A

Fission

42
Q

State the conditions during which the Mitochondria decides to undergo

Fission or Fusion

apoptosis

A

Fission

43
Q
They recognize epitopes (antigenic determinants) that are displayed by cells 
possessing HLA (human leukocyte antigen: 

Null cells
B lymphocytes
Natural T killer cells
T lymphocytes

A

T lymphocytes

44
Q

The following are Linege specific Hematopoietic Growth Factors EXCEPT:

IL-6
IL-5
Erythropoietin
Thrombopoietin
M-CSF
G-CSF
A

IL-6

45
Q

Trace the Red Cell development by assigning letters to the following cells by order of appearance:

Polychromato-philic erythroblasts 
pro-erythroblasts 
basophilic erythroblasts 
erythrocytes 
reticulocytes
Ortho-chromatophilic erythroblasts
A
pro-erythroblasts - A
basophilic erythroblasts - B
Polychromato-philic erythroblasts - C
Ortho-chromatophilic erythroblasts-D
reticulocytes-E
erythrocytes-F
46
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

cell membrane

A

both

47
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

membrane-bound nucleus

A

euk

48
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

multicelular organisms

A

euk

49
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

chromatin material

A

both

50
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

membrane bound organelles

A

euk

51
Q

Compare Prokaryotic versus Eukaryotic Cell: (you can choose more than one answer.)

unicellular organisms

A

both

52
Q

The leukocyte with the longest lifetime

lymphocyte
eosinophil
monocyte
basophil
neutrophil
A

lymphocyte

/???monocyte

53
Q

These cells DO NOT arise from Monocytes as their precursor:

mast cells
osteoclasts
microglia
macrophages

A

mast cells

54
Q

Which of the following contents of the Neutrophilic granules can degrade the components of bacterial cell walls?

gelatinase
defensins
collagenase
cathepsins
myeloperoxidase
lysozyme
A

lysozyme

55
Q

Senescent or worn out RBCs displaying swelling or other shape abnormalities are recognized and removed from circulation, mainly by macrophages of the following organs:

liver
2nd, 4th, & 5th choices only
1st, 2nd & 3rd choices only
All of the above
spleen
bone marrow
1st, 2nd, & 5th choices only
lymph node
adrenals
A

1st, 2nd & 3rd choices only

LIVER, SPLEEN, BONE MARROW

56
Q

Functions of Interleukins

interleukin-3

acts on PHSC, CFU-S, & myeloid progenitor cells
acts on CFU-Ly

A

acts on PHSC, CFU-S, & myeloid progenitor cells

57
Q

Functions of Interleukins

interleukin-7

acts on PHSC, CFU-S, & myeloid progenitor cells
acts on CFU-Ly

A

acts on CFU-Ly

58
Q

Synthesis of Proteins involves the following steps:

DNA REPLICATION
TRANSCRIPTION
TRANSLATION
first 2 only
last 2 only
A

last 2 only

59
Q

This cell could divide more rapidly, producing large numbers of differentiated cells:

mature cells
stem cells
committed progenitor cells

A

committed progenitor cells

60
Q

Which contents of the Eosinophils act to kill parasitic worms or helminths?

major basic proteins
eosinophilic peroxidase
arginine-rich factor
1st 2 choices only
all of the above
Other:
A

1st 2 choices only

61
Q

Plasma contains proteins in the following decreasing order of quantity:

Regulatory Proteins-Globulin-Albumin-Fibrinogen
Globulin–Fibrinogen-Regulatory Proteins-Albumin
Albumin-Globulin-Fibrinogen-Regulatory Proteins
Globulin-Albumin-Fibrinogen-Regulatory Proteins

A

Albumin-Globulin-Fibrinogen-Regulatory Proteins

62
Q

Give the roles of the following parts in the cell:

Inclusions

A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide

A

A. storage forms of nutrients, crystals, & pigments

63
Q

Give the roles of the following parts in the cell:

Peroxisomes

A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide

A

C. contain catalase to break down hydrogen peroxide

64
Q

Give the roles of the following parts in the cell:

Proteasomes

A. storage forms of nutrients, crystals, & pigments
B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins
C. contain catalase to break down hydrogen peroxide

A

B. degrade individual molecule of denatured or nonfunctioning polypeptide or proteins

65
Q

This CORRECTLY states regarding each Golgi apparatus (complex):

A. It has a convex entry face, known as the cis face closer to the rough endoplasmic reticulum
B. Its exit face is concave, known as the medial face oriented toward the cell membrane
C. Between the entrance and the exit faces are intermediate cisternae, known as the trans face
D. It is composed of a cluster of vesicles, tubules, and flattened membrane-bounded cisternae

A

D. It is composed of a cluster of vesicles, tubules, and flattened membrane-bounded cisternae

66
Q

The delta granules of platelets contain the following EXCEPT:

ATP
platelet derived growth factor
ADP
serotonin

A

platelet derived growth factor