19 Pharmacology - Quizzes Flashcards

1
Q

What does the term indication mean in terms of drugs?

A

That the drug is specific (indicated) for these conditions
The uses the drugs can be applied for.

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2
Q

What does the term contraindication mean?

A

That the drug is NOT to be taken by individuals with a certain condition eg pregnancy

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3
Q

What effect can grapefruit juice have on drug metabolism?

A

Inhibits CYP450 enzymes therefore affecting the metabolism of 50% of drugs

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4
Q

What does the term iatrogenic mean?

A

Induced by a medical practitioner

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5
Q

Name TWO ways of administering a drug that bypasses the first pass effect.

A

Sub-lingually
Injection

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6
Q

What does an agonist drug do?

A

Binds to cell receptors and stimulates activity

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7
Q

What does an antagonist drug do?

A

Binds to cell receptors and blocks the reaction

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8
Q

What is meant by a placebo? What percentage of
medications have been shown to have a placebo effect?

A

Placebo is a substance with no active material that promotes a positive reaction due to the belief of the patient.
30% of medications show this effect

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9
Q

Metformin is often used in the management of ……..

A

T2 diabetes mellitus

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10
Q

Allopurinol is often used in the management of ……..

A

Gout (prevention)

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11
Q

Simvastatin is a ……. lowering drug.

A

cholesterol

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12
Q

Diazepam is used in the management of ……..

A

anxiety

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13
Q

Diclofenac is an example of a ……..

A

NSAID

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14
Q

The names of beta-blocker drugs tend to end in -……..

A

ol

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15
Q

An opioid analgesic works on the pain pathway in the …….

A

CNS

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16
Q

Diuretics act on the ……….. to increase …………..
excretion. A common side effect is the loss of ………..s.

A

kidney
water
mineral salts

17
Q

Prednisolone is an example of a ……..

A

Corticosteroid

18
Q

Ranitidine (Zantac) is classed as a H2 receptor …….-ist.

A

antagon

19
Q

Explain what is meant by a loading dose.

A

A high intial dose to bring the drug level into the theraputic range in the body

20
Q

Give FOUR ways in which a drug can be administered.

A
  1. Orally
  2. Sub-lingually
  3. Injection
  4. Suppository