18 facial pain Flashcards
causes of bell plasy
HSV/VZV reactivation, demyelination, nerve edema.ischemia, autoimmune damage, vasospasms of nerve-feeding vessels
rapid onset of bilateral facial paralysis consider what
guillain-barre and uveroparotid fever (sarcoid)
most freq distribution of trigeminal neuralgia
V2/V3
common trigger point for trigeminal neuralgia
nasolabial fold
1st line tx for trigeminal
carbamazepine (anticonvulsant)
neurosurgery complications
facial dysesthesia and anesthesia dolorosa (numbness/pain)
glossopharyngeal neuralgia what’s affected
9th nerve (tonsil radiating to ear)
pain felt in ear neuralgia
tympanic plexus – ddx from TMD
trigger point for glossopharyngeal neuralgia
in ear canal
postherpetic neuralgia timeline
persists 1-6 months after onset of rash
postherpetic vs trigeminal
postherpetic burns w episodic stabbing
tactile allodynia
light touch elicits pain
postherpetic neuralgia
age for postherpetic neuralgia
50% of pts over 50 and 75% of pts over 75
atypical facial pain characteristic
drawing aching or pulling pain
hot spot on bone scan – increased temperature, tenderness, or marros activity
cluster headache clinical, cause, demographics
pain of midface and upper face, esp around eyes attacks in temporal groups vascular cuase 80% smokers \+ fmailial influence
cluster headache aka
horton’s syndrome, histaminic cephalgia, migrainous neuralgia
alarm clock headache
cluster – same time everyday
cluster headahce vs migraine
migraine has aura and pt is reclusive
vs cluster – no aura and hyperactive
paroxysmal hemicrania characteristics
attacks last 2-30 min, up to 40x /day
high freq, short attacjs, responds to indomethacin
hemicrania continua
unilateral, chronic, daily similar to cluster
responds to indomethacin
chronic paroxysmal hemicrania aka and cayse
sjastaad syndrome
congestion of conjunctival blood vessles and increased intraocular pressure
attacks last 2-30 min, up to 40x /day
high freq, short attacjs, responds to indomethacin
paroxysmal hemicrania
migraine characteristics
paroxysmal, unilateral, 4-72h
migraine cause
vasoconstriction of brain arteries 2/2 serotonin reduction –> ischemia and dilation
aura characteristic of
migraine
visual hallucination before pain
sparks (scintillation), partial blindness, loss of light perception (scotome), loss of ability to express thoughts (aphasia)
temporal arteritis aka and cause
giant cell arteritis, cranial arteritis
multifocal autoimmune vasculitis of temporal artery
headache coincinding with heartbeat
headache coincinding with heartbeat
temporal arteritis
temporal arteritis oral symptoms
jaw claudication (pain w mastication), pain wearing hats (pressure), blindness
generalized muscle ache and stiffness after headache attack
polymyalgia rheumatica
temporal arteritis
temporal arteritis histo
chronic inflammation of tunica intima and media, narrowing of lumen from edema and prolif of tunica intima, necrosis, giant cells
chronic inflammation of tunica intima and media, narrowing of lumen from edema and prolif of tunica intima, necrosis, giant cells
temporal arteritis
myasthenia gravis mechanism
autoimmune attack on ACh receptors w progressive fatigue of skeletal muscle
pts have thymus hyeprplasia or thymoma and at least 1 other autoimmune diosrder
myasthenia gravis clinical
subtle but progressive weakness, most noted in head and neck
inability to focus eye, drooping eyelid (ptosis), double vision (diplopia), dysphagia, dysarthria (slurred speeech), difficulty chewing
jaws hang open
inability to focus eye, drooping eyelid (ptosis), double vision (diplopia), dysphagia, dysarthria (slurred speeech), difficulty chewing
jaws hang open
myasthenia gravis
myasthenia gravis diagnosis
elevated serum ACh receptor antibodies
elevated serum ACh receptor antibodies
myasthenia gravis
myasthenia gravis histo
degenerated muscle fibers – smaller, lose rounded cross-section look
degenerated muscle fibers – smaller, lose rounded cross-section look
myasthenia gravis
neurodegenerative disorders w progressive weakness and mm wasting
progressive muscular atrophy
progressive bulbar palsy
amyotrophic lateral sclerosis
most common lethal AR disorder
progressive muscular atrophy
(SMN gene)
childhood; no facial involvement
SMN gene
progressive muscular atrophy – AR
childhood; no facial involvement
progressive bulbar palsy demographic and onset
children/young adults
starts w dysphagia
atrophy of facial muscles
amyotrophic lateral sclerosis aka, demographic
Lou Gehrig dz
middle age
amyotrophic lateral sclerosis presentation
leg stiffness (one affected more than the other – dragging leg)
fasciculation (small synchronous muscle contractions)
bulbar paralysis – dysfx of mm controlled by medulla oblonfata in late LAS
dysfx of mm controlled by medulla oblonfata
bulbar paralysis, late ALS
leg stiffness/dragging
ALS
fasciculations
small synchronous muscle contractions in ALS
small synchronous muscle contractions
fasciculations, ALS
immune response to ACE inhibitor
scalded mouth syndrome
scalded mouth syndrome what could case
immune response to ACE inhibitor
alternative names for burning mouth syndrome
glossopyrosis, stomatopyrosis, glossodynia, stomatodynia
upper resp infx taste/smell
temporary dysgeusia
cns tumor taste/smell
dysgeusia
trauma/tumors/peripheral nerve inflammation
transient hypogeusia
taste hallucination
migraine, bell palsy, VZV
hemiageusia
ageusia of 1/2 tongue – ischemia and infarction of brainstem
periodontisis and taste
salty taste, high NaCl content of crevicular fluids
flavor and smell
75% of flavor info in smell
aberran odor perception
parosmia
complain of foul or rancid taste
phantom taste
dysgeusia in absence of food stimulus
frey syndrome manifest
facial flushing/sweating along auriculotemporal nerve in response to gustatory stimuli
frey syndrome casues
parotid absess, surgery (40% parotidectomy), trauma, diabetes, forceps delivery
injury to nerve
chin and submental gustatory sweating
chorda tympani syndrome - dx of submandibular gland
gustatory lacrimation
facial nerve injury; crocodile tears
TMJ osteoarthritis imaging
obliteration of joint space, exostoses/osteophytes, subchondral cysts, ossicles in synovial membrane
stages of rheumatoid arthritis
autoiimune destruction of joints
starts as synovitis –> then pannus (reative m/ph-laden fibroblastic proliferation from synovium onto joint surface)
reative m/ph-laden fibroblastic proliferation from synovium onto joint surface
pannus, rheumatoid arthritis
most affected joint in osteoarthritis
hips
most affected joints in rheumatoid arthritis
hands and feet
hips least affected
joint shape in rheumatoid arhtritis
anvil
tmj in rheumatoid arthritis
75%
usually bilateral
flat condylar head
nontender subcutaneous growth near joint
rhematoid nodules
amorphous eosinophilic necrosis surrounded by thick layer of mononuclear cells
rheumatoid labs
80% elevated RF, 50% ANAs
histo rheumatoid arthritis
rice bodies: small white villi made of cellular debris admixed w fibrin/collagen
rice bodies
small white villi made of cellular debris admixed w fibrin/collagen
rheumatoid arthritis
anklysoing spondylitis
systemic rheumatic disease
HLA B27 in 90% of pts
risk factors and sex predilection for bell palsy
Risk factors:
Obesity /Pregnancy / preeclampsia / Diabetes /HT/
Infection 30% have HSV
F > M
guillain barre cause and presentation
autoimmune
aka landry’s paralysis
damage to PNS - bilateral
mm weakness: behins ain feet and hands
acute polyneuropathy (1st to appear)
numb/tingling pain
respiratory failure
diagnostic clinical features of trigeminal neuralgia
refractory period
giant cell arteritis demographic
> 50yr, scandinavian/north european/F
HLA-DR4
complication of giant cell arteritis
blindness
pain chewing in masseter and temporalis
aorta ffected in 50%
labs in giant cell arteritis
elevated ESR , C-reactive protein, and platelet count
HLA-DR4
giant cell arteritis
Polymyalgia Rheumatica:
Symptom found in Giant Cell Arteritis (GCA)
Morning stiffness in neck, shoulder, pelvis
narrowing of joint space: OA vs RA
OA narrow
RA narrow only if ankylosis
subchondral cysts
OA; Large degenerative space beneath cartilage (Radiolucent)
OA in joint what find
Subchondral cysts: Large degenerative space beneath cartilage (Radiolucent)
Ossicles: metaplastic bone
Chondral bodies: Multiple hyaline cartilage granules
Narrowing of joint space
pannus
RA
Fibroblastic proliferation / Macrophage laden
Polyarthralgia:
RA
ankylosis RA or OA
RA
anvil joints
RA
joints in RA
anvil
RA in joint space
rice bodies, pannus, anvil joints, ankylosis
skin in RA
rheumatoid nodules (20%) beneath skin near affected joints, pathognomonic
labs for RA
ACPAs * Specific*
80% RF
50% ANA
90% elevated ESR
OA vs RA cause, age, location
OA: Degenretaive due to age >50yrs Hips, knees, spine (weight bearing joints)
RA: Autoimmune 25-35yrs Bilateral , symmetrical involvement of small joints, hands and feet
heberden
OA nodules at distal or interphalanges joints. Due to calcific spurs (osteophytes) from repeated trauma
crepitation RA or OA
OA
swan neck deformity
and ulnar deviation
RA
pain in morning better later
RA
pain worse toward evening
OA
rice bodies
RA