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AIIMS > 17.6.2013(pediatrics)40 > Flashcards

17.6.2013(pediatrics)40 Flashcards

0
Q

Epilepsy in autism

A

1/5 to 1/3

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1
Q

Mental retardation in children with autism

A

75%

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2
Q

Onset of autism

A

Before age of 3 years

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3
Q

Specific marker for autism

A

Two or more trophoblastic inclusions

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4
Q

3 essential criteria for diagnosis of autism

A

Impaired social interaction
Impaired communication
Restricted, repetitive range of interests,behaviours,activities

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5
Q

Seizure disorder with loss of language skills

A

Landu kleffner syndrome

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6
Q

Age of onset of landu kleffner syndrome

A

5 1/2 years

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7
Q

Landu kleffner syndrome is common in

A

Boys

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8
Q

DD for landu kleffner syndrome

A

Autism

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9
Q

DOC for landu kleffner syndrome

A

Sodium valproate

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10
Q

CT and MRI in landu kleffner syndrome

A

Normal

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11
Q

Rx of Lennox gestaut syndrome

A

Ketogenic diet

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12
Q

Rolandic epilepsy

A

Benign childhood partial epilepsy with centrotemporal spikes

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13
Q

Age of onset of rolandic epilepsy

A

9-10yrs

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14
Q

Presentation of rolandic epilepsy

A

Partial seizures

Motor and sensory symptoms are often confined to face

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15
Q

Prognosis of rolandic epilepsy

A

Excellent

Spontaneous remission after 14-16yrs

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16
Q

Rx of rolandic epilepsy

A

Carbamazepine for 2 years

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17
Q

Rasmussen encephalitis

A

Subacute inflammatory encephalitis

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18
Q

Rasmussen encephalitis presents as

A

Epilepsia partialis continua

19
Q

Cause of Rasmussen encephalitis

A

Autoantibodies that stimulate glutamate receptors

20
Q

Prognosis of Rasmussen encephalitis

21
Q

Progressive Myoclonic epilepsy

A

Lafora disease

22
Q

Mental deterioration is characteristic feature of

A

Lafora disease

23
Q

Presentation of Lafora disease

A

Initially GTCS,later Myoclonic jerks

24
Q

Lafora bodies are seen in

A

Eccrine sweat gland duct cells

25
Q

Gene involved in Lafora disease

A

6p

Codes for tyrosine phosphatase

26
Q

Cause of renal artery stenosis in young

A

India(Takayasu)

West(Fibromuscular dysplasia)

27
Q

Bleeding from umbilical stump suggests

A

Factor XIII deficiency

28
Q

Test to detect factor XIII deficiency

A

Clot stability in 5M urea

29
Q

Why Von willi brand disease pts don’t present in neonatal period

A

Plasma Von willi brand levels are high(maternal)

30
Q

Presentation of factor XIII deficiency

A

Bleeding
Delayed wound healing
Infertility in males
Abortion in females

31
Q

Physiological jaundice,duration

A 
Phase 1
 5 days(term infants) 12mg/dl
 7 days(preterm infants) 15mg/dl
Phase 2
 Values decline to 2mg/dl which lasts for 2 weeks
32
Q

Breast feeding jaundice,onset

33
Q

Cause of breast feeding jaundice

A

Reduced feed
Dehydration
Unconjugated hyperbilirubinemia

34
Q

Breast milk jaundice,onset

A

4-7 days

May continue till 3rd month

35
Q

Cause of breast milk jaundice

A

Inhibitors of conjugation present in breast milk
Beta pregananediol
Free fatty acids

36
Q

Primary prophylaxis should be given within

37
Q

Drugs not used for primary prophylaxis

A

Tetracyclines

Sulpha drugs

38
Q

Secondary prophylaxis of rheumatic fever

A

Prevention of colonisation of URI in pts who already had a previous attack of RF or established RHD

39
Q

Drugs used for primary prophylaxis of RF

A 
Benzathine pencillin 1.2M units i.m single dose
Penicillin V for 10 days
Erythromycin
Cephalexin
Cefadroxil
Clindamycin
Azithromycin
Erythromycin
Clarithromycin
40
Q

Secondary prophylaxis duration

A

21 years of age or 5 years after the last attack of RF whichever is later
If heart disease is present life long prophylaxis or atleast till 40 yrs of age

41
Q

Secondary prophylaxis,drugs

A

Benzathine pencillin 1.2MU every 3-4 weeks

Pencillin V 500mg bd

42
Q

Secondary prophylaxis in penicillin allergic pt

A

1.SULPHADIAZINE
Penicillin and sulfonamide allergy
Macrolides

43
Q

Type of rickets not associated with myopathy

A

X linked hypophosphatemic rickets

44
Q

Diff btw hypophosphatemic and calcium deficient rickets

A 
No tetany
No dental enamel hypoplasia
No profound myopathy
No rachitic rosary and Harrison sulcus 
In hypophosphatemic rickets

AIIMS (13 decks)

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