17. Veins, Capillaries and Lymphatics Flashcards

1
Q

What is filtration of capillaries and what main 2 force determine the rate?

A

Net movement of fluid

  1. Capillary blood pressure
  2. Plasma protein colloid osmotic pressure
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2
Q

What is the average outward force of capillaries?

A

17mmHg

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3
Q

What is the average inwards force of plasma protein colloid osmotic pressure in capillaries?

A

28mmHg

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4
Q

Why might a capillary become more permeable?

A

Histamine, bacterial infection, prolonged ischaemia or burns

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5
Q

What is hydrostatic pressure?

A

Weight of a column of water

Pressure increases as you go beneath heart level

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6
Q

Effects of gravity below heart level

A

Veins distend due to increased transmural pressure
Temporary fall in venous return
Muscle pump and valves break up columns of blood when moving

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7
Q

Effect of gravity above heart level

A

No effect as deep veins in brain stay open due to non-collapsable structure even at negative pressure

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8
Q

What happens when you stand up?

A

Immediate pooling of blood in legs
Fall in venous return
Fall in cardiac output
Baroreceptors detect fall in BP

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9
Q

Describe the postural adaptation response

A

Baroreceptors detect fall in BP
Increase HR and cardiac output
Vasoconstrict to mobilise venous blood

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10
Q

What is postural hypotension?

A

Veins constrict less, causing pooling of blood

Results in fainting due to decreased CO and BP

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11
Q

What happens at positive G forces?

A

Black out

Blood pools in feet resulting in a lack of cerebral flow

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12
Q

What happens at negative G forces?

A

Red out

Blood rushes to the head

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13
Q

What happens after prolonged exposure to zero gravity?

A

Weakened heart and atrophy

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14
Q

What does Central Venous Pressure measure?

A

Right atrial pressure

Shows right cardiac function and dehydration

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15
Q

What does the Jugular Venous Pressure give an estimate of?

A

Central Venous Pressure

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16
Q

What does portal hypertension result in?

A

Development of shunt vessels that bypass the liver

17
Q

Why could the adaptation to portal hypertension cause morbidity?

A

Shunt vessels bleed easily

Toxic substances bypass liver and damage other organs

18
Q

What effect does lymphatic pumping have on loose tissues?

A

Causes slightly negative interstitial pressure

19
Q

What is damage, loss or block of lymphatics called?

A

Lymphoedema

20
Q

What four things favour venous return?

A
  1. Pressure gradient to the heart
  2. Pumping of skeletal muscle
  3. Negative intrathoracic pressure when inspiring
  4. Venoconstriction