17. Leveraging Artificial Intelligence in Drug Development Flashcards

1
Q

Machine learning

A

a “thing-labeler” & categorizes new things (input: the description of something–> output: what label that that thing should get)

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2
Q

Ineffable

A

too extreme to be described in words
- Machine learning and AI “automates the ineffable” & is good at finding patterns in data

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3
Q

Found ____ protein-protein interactions in COVID

A

332

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4
Q

Humans have about ______different proteins and ______ interactions between them

A

20,000
200 million

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5
Q

AI pharmacokinetic inputs

A
  • physiology variables (blood flow, body fat composition, etc)
  • Drug’s chemical properties
  • Drug-specific preclinical information
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6
Q

AI pharmacokinetic outputs

A
  • Absorption
  • Distribution
  • Metabolism
  • Elimination
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7
Q

HumMod

A

“the most complete mathematical model of human physiology ever created”

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8
Q

in silico clinical trials

A

clinical trials inside a computer

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