16.3 Flashcards
hormones
-produced in glands which secrete directly into blood
-carried in blood plasma to target cells
-effective in low concs
-widespread and long-lasting
Adrenaline mechanism
-adrenaline binds to protein receptor within csm of liver cell
-causes protein to change shape on inside of membrane
-activates enzyme adenyl cyclase
-ATP converted to cyclic AMP
-cAMP acts as second messenger and binds to protein kinase enzyme, changing its shape and activating it
-active protein kinase enzyme catalyses conversion of glycogen to glucose
-glucose moves out of liver cell by facilitated diffusion into blood
pancreas
produces enzymes protease amylase and lipase
produces hormones insulin and glucagon
which cells make up pancrease
endocrine cells grouped together into islets of Langerhans
a cells
larger and produce glucagon
b cells
smaller and produce insulin
glycogenesis
conversion of glucose into glycogen
glycogenolysis
breakdown of glycogen to glucose
gluconeogenesis
production of glucose from sources other than carbohydrates(e.g. glycerol and amino acids)
too high blood glucose
lowers water potential of blood
-osmotic problems
-dehydration
too low blood glucose
lack of respiration
cells deprived of energy and die
3 factors that influence bgc
- diet
- hydrolysis in the small intestine of glycogen
- gluconeogenesis
b cells and high bgc
- have receptors that detect stimulus of rise in bgc
-secrete insulin directly into blood
-insulin binds with glycoprotein receptors on csm of red blood cells
-glucose transport carrier proteins change tertiary structure and open, allowing more glucose into cells by facilitated diffusion
-number of glucose carrier proteins increase on csm(vesicles fuse with csm to help)
-activation of enzymes that convert glcose to glycogen and fat
lowered bgc
- increases rate of absorption of glucose into cells
-increases respiratory rate of cells
-increase rate of conversion of glucose into glycogen in cells of liver and muscles
-increases rate of conversion of glucose to fat
a cells and low bgc
- a cells detect fall in bgc and secrete glucagon into blood
-glucagon attaches to specific protein receptors on csm of liver cells
-activates enzymes that convert glycogen to glucose
-activate enzymes involved in conversion of amino acids and glycerol into glucose