12.3 oxidative phosphorylation Flashcards
oxidative phosphorylation
energy of electrons within hydrogen atoms(in NADH and FADH) is conserved in formation of ATP
site of oxidative phosphorylation
mitochondria cristae
adaptations of mitochondria for op
- occur in great numbers in metabolically active cells
- have densely packed cristae for greater SA of enzymes and proteins
electron transfer chain
- hydrogen atoms from glycolysis and krebs cycle combine with NAD and FAD
-reduced NAD AND FAD donate electrons of hydrogens to the first molecule in ETC
-electrons pass along chain of electron transfer carrier molecules in series of oxidation-reduction reactions
-electrons release energy as the flow along chain, causing active transport of protons across inner mitochondrial membrane and inter membranal space
- H+ ions build in inter membranal space before diffusing back into mitochondrial matrix through ATP synthase channels(phosphorylates one ADP per H+ ion)
-at end of chain, electrons combine with H+ and O2(final electron acceptor) to form water
ETC energy release
move down energy gradient, allowing energy to be released gradually and usefully
-greater energy released in single step, the more its released as heat and not useful purposes
alternative respiratory substrates
lipids and proteins can be used
-doesn’t need to be converted to carb
lipid respiration
hydrolysed to glycerol and fatty acids
glycerol phosphorylated to triose phosphate
-enters glycolysis pathway and krebs cycle
fatty acid broken into 2C to acetyl CoA
oxidation produces 2C and many H atoms
-lipids release more than double energy of same mass of carb
protein respiration
protein hydrolysed to aminoa cids
amino group removed before entering respiration pathway at different points depending on C number