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PT B1T1 > 15 RAS inhibitors > Flashcards

15 RAS inhibitors Flashcards

1
Q

mineralcorticoid receptor antagonists

A

spironolactone

eplerenone

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2
Q

name the ACEis

A

captopril, enalapril, lisinopril, fosinopril

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3
Q

name the ARBs

A

losartan, valsartan

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4
Q

aliskiren

A

renin inhibitor

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5
Q

ACEi affect on bradykinin and PGIs

A

“increases bradykinin and PGIs

ACE normally degrades bradykinin which synthesizes PGI

by inhibiting ACE, both are upregulated –> watch out for angioedema!
“

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6
Q

ARB adverse effects

A

dizzy, hypotension, hyperkalemic

teratogenic

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7
Q

natriuretic peptides

A

increase natriuresis

vasodilate

increase vagal tone/decreases SNS

pretty much reverse RAS

ANP/BNP, CNP act on different receptors

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PT B1T1 (18 decks)

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