15 RAS inhibitors Flashcards
1
Q
mineralcorticoid receptor antagonists
A
spironolactone
eplerenone
2
Q
name the ACEis
A
captopril, enalapril, lisinopril, fosinopril
3
Q
name the ARBs
A
losartan, valsartan
4
Q
aliskiren
A
renin inhibitor
5
Q
ACEi affect on bradykinin and PGIs
A
“increases bradykinin and PGIs
ACE normally degrades bradykinin which synthesizes PGI
by inhibiting ACE, both are upregulated –> watch out for angioedema!
“
6
Q
ARB adverse effects
A
dizzy, hypotension, hyperkalemic
teratogenic
7
Q
natriuretic peptides
A
increase natriuresis
vasodilate
increase vagal tone/decreases SNS
pretty much reverse RAS
ANP/BNP, CNP act on different receptors