15 - Rapid Disease Detection Flashcards
Infectious disease surveillance
- Collecting, analysis and use of infectious disease data to help inform public health
- Should be large population data
- Inclusive of all factors that effect disease transmission
- Should be ongoing
- Should be systemic
- Should be disseminated
Disease (outbreak) investigation
- Should be responsive (react quickly)
- Opportunistic (wide scope)
- Sufficient skilled staff for analysis
- Info disseminated to stakeholders
Value of infectious disease surveillance
- Monitors changes in infectious disease (e.g. AMR)
- Asses effectiveness of prevention
- Helps determine allocation of resources for prevention
- Identification of high risk populations
Example of professions included in a disease surveillance program team
- Epidemiologists
- Infectious diseases experts
- Mathematical modelers
Scope of surveillance plan
- Local, state, national, regional, global
- Determine info to be collected
- How to collect data
- How to analyse data
- How to disseminate data
- How to track data
- How to review success or failure
Data collection
- Source of data (hospitals, research facilities, diagnostic facilities)
- Means of data collection (proactive or retrospective)
- Handling of data
- Availability of data
Proactive data collection
Real time collection
Retrospective data collection
Reporting in trends
What does the type of data collected depend on
The type of disease and the function of surveillance
Mechanisms of predicting disease emergence
- Seasonality
- Tracking globally
- Use of sentinel animals
- Monitoring and controls in food production
Use of Sentinel animals
- Used to provide early warning of initiation of of zoonotic infections in areas of human populations
- Move from sylvatic to urban cycles
- Important for domestic animals
Role of diagnostic lab
- Early warning signals (unexpected increase in cases)
- Outbreak response and management
- Rapid collation of data
- Trend monitoring
- Intervention evaluation
what do methods of analysis of data depend on
- Type of data (sequence vs diagnostic)
- Volume of data
- Resources and expertise available
Challeneges in how to disseminate data
- Need to reach at risk population
- Need to educate health workers
- Need to provide accurate data rapidly
Internet and mobile phones
- Allow for free rapid dissemination of surveillance information
- Also allows for rapid dissemination of fake news
Future of disease surveillance
Point of care tests and mobile phones will transform detecion process
Diagnostics using mobile phones
- Nanosensors for detection of disease
- Can be used to penetrate biofilms