1.4Brain Disease Flashcards
Symptoms of Parkinson’s disease
Small hand writing
Shuffling gait
Stooped posture
Muscle rigidity
Peak age of Parkinson’s disease
55-60
What part of the brain does Parkinson’s disease affect
The basal Ganglia
What is the basal ganglia
Group of sub cortical nuclei
What is the role of the basal ganglia
Provides fine motor control
What chemical is depleted in the striatum that causes Parkinson’s disease
Dopamine
Treatment for Parkinson’s disease
Drugs to increase brain dopamine
How does L-DOPA work
Enters brain then converts to dopamine
Side effects of L-DOPA
Uncontrollable movement
What is Huntington’s disease
Disease causing involuntary muscle jerk
Peak age of Huntington’s disease
30 - 45
treatment for Huntington’s disease
No effect treatment
What is addiction
Excessive use of a substance for non medical reasons
Brings damage to relationships
when animals receive rewards. What chemical is released
Dopamine
Positive symptoms of schizophrenia
Hallucinations
Delusions
Negative symptoms
Behaviour withdrawals
Cognitive symptoms of schizophrenia
Disturbance of attention + cognition
How does chlorpromazine work in treating schizophrenia
Chlorpromazine is an antagonist st dopamine receptors
- blocks dopamine in the brain
The dopamine hypothesis
Schizophrenia is linked to increased dopamine
How do atypical drugs differ to typical drugs
Newer
Less side effects
Both dopamine and serotonin receptors
