14.6 DNA Repair Flashcards
proofreading
function of DNA pol in which it reads the
newly added base before adding the next one
mismatch repair
type of repair mechanism in which
mismatched bases are removed after replication
nucleotide excision repair
type of DNA repair mechanism in which the wrong base, along with a few nucleotides upstream or downstream, are remove
Mutations
variations in the nucleotide sequence of a genome, can also occur because of damage to DNA
Induced mutations
result from an exposure to chemicals, UV rays, x-rays, or some other environmental agent
Spontaneous mutations
they are a result of natural reactions taking
place within the body
. Transition substitution
a purine or pyrimidine being replaced by a base of the same kind;
for example, a purine such as adenine may be replaced by the purine guanine
Transversion substitution
when a purine is replaced by a
pyrimidine or a pyrimidine is replaced by a purine