13.8 Pharmacology: Drugs and the GI system Flashcards

1
Q

What do Proton Pump Inhibitors (PPI) or H+/K+ ATPase Inhibitors do? What are they used for?

A

Decrease gastric acid secretion

Peptic ulcer disease

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2
Q

What are 2 examples of PPIs?

A

Omeprazole

Esomeprazole

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3
Q

What is the gold standard peptic ulcer disease treatment and why?

A

PPIs

Very effective and longlasting (kill enzyme until new synthesis)

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4
Q

What do H2-R’ Antagonists do and what are they used for?

A

Decrease gastric acid secretion

Peptic ulcer disease

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5
Q

What is an example of an H2-R’ Antagonist?

A

Ranitidine

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6
Q

What do antacids do? What are they use for?

A

Neutralise gastric acid

PUD

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7
Q

What is an example of an antacid?

A

Magnesium hydroxide

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8
Q

What does a spasmolytic do? What is it used for?

A

Muscarinic receptor antagonist (SLUD decrease)

PUD

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9
Q

What is an example of a spasmolytic?

A

Hyoscine butylbromide

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10
Q

What is an example of a Muscarinic Receptor Antagonist? What is it used for?

A

Hyoscine hydrobromide

Anti-emetic

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