13.8 Pharmacology: Drugs and the GI system Flashcards
What do Proton Pump Inhibitors (PPI) or H+/K+ ATPase Inhibitors do? What are they used for?
Decrease gastric acid secretion
Peptic ulcer disease
What are 2 examples of PPIs?
Omeprazole
Esomeprazole
What is the gold standard peptic ulcer disease treatment and why?
PPIs
Very effective and longlasting (kill enzyme until new synthesis)
What do H2-R’ Antagonists do and what are they used for?
Decrease gastric acid secretion
Peptic ulcer disease
What is an example of an H2-R’ Antagonist?
Ranitidine
What do antacids do? What are they use for?
Neutralise gastric acid
PUD
What is an example of an antacid?
Magnesium hydroxide
What does a spasmolytic do? What is it used for?
Muscarinic receptor antagonist (SLUD decrease)
PUD
What is an example of a spasmolytic?
Hyoscine butylbromide
What is an example of a Muscarinic Receptor Antagonist? What is it used for?
Hyoscine hydrobromide
Anti-emetic