13 - 14 weeks // Stochastic Effect Flashcards

1
Q

The probability of the effect increases with increasing dose.

A

Stochastic Effect

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2
Q

It is the studies of large numbers of people exposed to a toxic substance require considerable statistical analysis.

A

Epidemiologic Studies

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3
Q

Epidemiologic studies of people exposed to radiation are difficult because:

The dose usually is ___ _____ but is presumed to be ___ and the frequency of response is ____ ___.

A

Epidemiologic studies of people exposed to radiation are difficult because:

The dose usually is not known but is presumed to be low and the frequency of response is very low.

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4
Q

The irradiation of blood forming organs can produce hematologic depression as a deterministic response or leukemia as a stochastic response.

A

Chromosomes

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5
Q

Chromosome damage in the circulating lymphocytes can be produced as both a _____ _____ and a _____ _____.

A

Chromosome damage in the circulating lymphocytes can be produced as both a deterministic effect and a stochastic effect.

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6
Q

Individuals accidentally exposed with ___ ____ doses continue to show chromosome abnormalities for __ ____ after the exposure.

A

Individuals accidentally exposed with high radiation doses continue to show chromosome abnormalities for 20 years after the exposure.

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7
Q

Year when cyclotron used to accelerate charged particle to very high energies.

A

1932

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8
Q

Year when every university physics department had one and was engaged in high energy experiments.

A

1940

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9
Q

First cataract report

A

1949

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10
Q

Year when several hundred cases of cataracts were reported

A

1960s

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11
Q

Radiation induced cataracts occur in the _____ ___ of the lens.

A

Radiation induced cataracts occur in the posterior pole of the lens.

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12
Q

Radiosensitivity of the eyes is ___ dependent.

A

Radiosensitivity of the eyes is age dependent.

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13
Q

___ let radiation have ___ rbe for the production of cataracts.

A

High let radiation have high rbe for the production of cataracts.

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14
Q

__gyt (____rad) where cataracts develop in nearly 100% of those who are irradiated.

A

10gyt (1000rad) where cataracts develop in nearly 100% of those who are irradiated.

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15
Q

Threshold after an acute x-ray exposure is approximately __gyt (___rad).

A

Threshold after an acute x-ray exposure is approximately 2gyt (200rad).

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16
Q

The threshold after fractionated exposure is probably in excess of __gyt (____rad).

A

The threshold after fractionated exposure is probably in excess of 10gyt (1000rad).

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17
Q

Occupational exposures to the lens of the eye are ___ ___ to require protective lens shields for radiologic technologists.

A

Occupational exposures to the lens of the eye are too low to require protective lens shields for radiologic technologists.

18
Q

In computed tomography, the lens dose can be __mgyt (_rad).

A

In computed tomography, the lens dose can be 50mgyt (5rad).

19
Q

At worst, humans can expect a reduced life span of approximately 10 days for every 10mgyt.

Whereas, the average life shortening caused by occupational accidents amounts to 74 days, for radiation workers, life is shortened by only 12 days.

A

Life Span Shortening

20
Q

Nearly 100,000 died from the blast and early effects.

Another 100,000 received a high dose but survived.

The remainder received less than 10rad.

A

Atomic Bomb

21
Q

Radiation induced leukemia follows a _____ ______ dose - relationship.

A

Radiation induced leukemia follows a linear nonthreshold dose - relationship.

22
Q

Year when in Great Britain, patients with ankylosing spondylitis were treated with radiation to cure.

A

1940s to 1950s

23
Q

Most radiologist received doses ___ rad/year.

A

Most radiologist received doses100rad/year.

24
Q

20 years until patient cured started dying from ______.

A

20 years until patient cured started dying from leukemia.

25
Q

____ ___ ____ had received 100 to 4000 rad.

A

Spinal bone marrow had received 100 to 4000 rad.

26
Q

Relative risk from the study of leukemia was __:1.

A

Relative risk from the study of leukemia was 10:1.

27
Q

Radiation induced leukemia also can be reported for radiation induced ______.

A

Radiation induced leukemia also can be reported for radiation induced cancer.

28
Q

It has been shown to develop in three groups of patients whose thyroid glands were irradiated in childhood.

A

Thyroid Cancer

29
Q

Ann ___ Series and the ______ Series, they treated shortly after birth for enlarged thymus with up to ___ rad.

A

Ann Arbor Series and the Rochester Series, they treated shortly after birth for enlarged thymus with up to 500 rad.

30
Q

__ children natives of _____ Atoll in 1954, these children received radiation doses about __gyt (1200rad).

A

21 children natives of Rongelap Atoll in 1954, these children received radiation doses about 12gyt (1200rad).

31
Q

Two population groups have contributed an enormous quantity of data showing that radiation can cause ____ ______.

A

Two population groups have contributed an enormous quantity of data showing that radiation can cause bone cancer.

32
Q

72 bone cancers in about 800 workers have been observed in 50 years.

Relative risk was 122:2.

A

Radium Watch Dial Painters

33
Q

Patients treated with radium for _____ and ______.

A

Patients treated with radium for arthritis and tuberculosis.

34
Q

Additional studies have produced results suggesting that radiation induced ____ ____ developed in patients treated with x-rays for acute postpartum mastitis.

A

Additional studies have produced results suggesting that radiation induced breast cancer developed in patients treated with x-rays for acute postpartum mastitis.

35
Q

In breast cancer, the dose to patients range from 0.75 to __ Gyt.

The relative risk factor in this population was approximately 3:1.

A

In breast cancer, the dose to patients range from 0.75 to 10 Gyt. (75 to 1000rad)

The relative risk factor in this population was approximately 3:1.

36
Q

This was for many years treated by isolation in a sanitarium. During the patient’s stay, one mode of therapy was to induce a pneumothorax in the affected lung, this was done under non-image intensified fluoroscopy.

A

Tuberculosis

37
Q

In liver cancer, Thorium Dioxide (TH02) in a colloidal suspension known as _____.

A

In liver cancer, Thorium Dioxide (TH02) in a colloidal suspension known as thorotrast.

38
Q

In liver cancer, radiation that was emitted produced a dose in the ratio of approximately _______ of alpha, beta and gamma radiation, respectively.

A

In liver cancer, radiation that was emitted produced a dose in the ratio of approximately 100:10:1 of alpha, beta and gamma radiation, respectively.

39
Q

Early in the __ century, it was observed that approximately __% of workers in the Bohemian Pitchblende mines of Germany died of ____ _____.

A

Early in the 20th century, it was observed that approximately 50% of workers in the Bohemian Pitchblende mines of Germany died of lung cancer.

40
Q

4000 uranium miners have been observed and they have received estimated doses to lung tissue as high as __gyt.

A

4000 uranium miners have been observed and they have received estimated doses to lung tissue as high as 30gyt (3000 rad).

41
Q

The relative risk of lung cancer was approximately _:1.

A

The relative risk of lung cancer was approximately 8:1.

42
Q

This usually begins with the development of radiodermatitis.

A

Skin Cancer