128: Gonads Flashcards
small or absent testes, gynaecomastia, infertility, reduced libido, reduced hair, osteoporosis, Eunochoid body proportions is prepubertal.
Primary hypogonadism.
female phenotype, but amenorrhoea
foetal androgen deficiency ( male testosterone levels and XY chromosomes).
androgen excess from ovary
PCOS ( or ovarian tumour)
missing 46x chromosome, primary amenorrhoea, lymphoma of hands and feet, neck webbing, cubits valgus.
Turner’s Syndrome
what is cubits Valgus?
forearm is angled away from the body.
oestrogen secretion before 7-8 years in girls
precocious puberty
hypergonadotropic amenorrhoea in women
premature ovarian failure.
primary hypogonadism investigation findings…
low testosterone, elevated LH and FSH. Seminal analysis.
primary hypogonadism treatments…
testosterone replacement, infertility treatment, occasionally gonadotrophins, phosphodiesterase type V inhibitors. ( Sildenafil)
foetal androgen deficiency treatment…
orchidectomy and oestrogen replacement.
PCOS treatment
metformin, oral oestrogen/progesterone, infertility treatment.
ovarian tumour treatment…
oophorectomy
turner’s syndrome treatment…
oestrogen replacement. growth hormone in children.
precocious puberty treatment…
LHRH down regulates LH and FSH production.
premature ovarian failure treatment…
Oestrogen replacement. Donor ovum therapy
