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Nutrition > 106: GORD > Flashcards

106: GORD Flashcards

1
Q

What is Barrett’s Oesophagus?

A

Metaplasic mucosa forms where squamous sould be in the oesophagus cut to gastric acid damage

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2
Q

cells in the gastric body mucosa…

A

chief and parietal calls

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3
Q

glandular tumour nomenclature…

A

adenocarcinoma

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4
Q

smooth muscle tumour….

A

leiomyosarcoma

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5
Q

skeletal muscle tumour…

A

rhabdomyosarcoma

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6
Q

bone tumour…

A

osteosarcoma

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7
Q

cartilage tumour..

A

chondrosarcoma

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8
Q

fibrous tissue tumour…

A

fibrosarcoma

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9
Q

vascular tumour…

A

angiosarcoma

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10
Q

melanocytes tumour…

A

malignant melanoma

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11
Q

peptic ulcer symptoms

A

dyspepsia, weight loss, anorexia, IBS. GU - after meals, DU- 2-5h post meal/empty stomach

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12
Q

ulcer causes

A

NSAIDS ( reduce COX 1 levels - reduced protective prostaglandins)
Helicobacter Pylori ( antral gastritis cuases DU, pan gastritis - GU)
smoking
stress/diet/familial

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13
Q

how do proton pump inhibitors work?

A

inhibit H transport from parietal cells

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14
Q

what is Meckel’s Diverticulum

A

embryological malformation of distal ileum

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15
Q

What is Stevens-Johnson Syndrome?

A

autoimmune hypersensitivity disorder causing target skin lesions

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16
Q

What is achalasia?

A

condition affecting the nerves and muscles of the oesophagus - affecting swallowing.

17
Q

what do antacids do?

A

neutralise acid production

18
Q

what to alginates do?

A

reduce irritancy of acid

19
Q

what do sucralfates do?

A

promote mucosal defence via prostaglandin receptor

20
Q

what does metoclopramide and domperidone do?

A

gastric stimulant - peristalsis

21
Q

what do proton pump inhibitors and H2 receptor agonists do?

A

reduce acid production.

22
Q

name a sucralfate…

A

misoprostol

23
Q

name some H2 receptor agonists

A

ranitidine, nizatidine, famotidine, cimetidine

24
Q

name some proton pump inhibitors

A

omeprazole, lansoprazole, pantoprazole, esomeprazole

25
Q

treatment of h pylori

A

omeprazole, amoxicillin and clarithromycin

26
Q

constipation from antacids likely de due to

A

aluminium

27
Q

what should not be prescribed for a woman of childbearing age for acid reflux?

A

misoprostol

28
Q

what has a protective effect on gastrointestinal mucosa?

A

prostaglandins

29
Q

long term use of PPI is associated with

A

c diff, osterporosis, community acquired pneumonia

30
Q

which medications cause dyspepsia in some patients ?

A

calcium channel blockers

31
Q

ranitidine blocks the action of which substrate on the receptor?

A

histamine

32
Q

m3 receptors receive which substrate?

A

acetyl choline

33
Q

CCk2 receptors receive which substrate

A

gastrin

Nutrition (16 decks)

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