126 Skin and soft tissue infection Flashcards

1
Q

What important cells live in the epidermis?

A

keratinocyte
langerhands cell
melanocytes
sweat glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Disruption of the dermis results in what skin changes?

A

vesicles
bullae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What important cells are in the subcutaneous tissue

A

lymphatic drainage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Linear erythema tracking along vascular pathway ddx 2

A

phlebitis
lymphangitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pruritic snakelike lesions not particular tender ddx?

A

parasite - scabies, hookeworm, stronglyoides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are janeway lesions?

A

painless red purple or brown spots on hands or feet from septic embolic from IE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Painless discoloration of the palsm and soles ddx 2 important?

A

secondary syphilis
RMSfever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DDX petechiae and purpura

A

sepsis
mengingococcemia
kawasaki
gpa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is cellulitis?

A

inflamm cond of skin and subcut tissue caused by bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cardinal feature of cellulits?

A

inflamm with incr local blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cellulitis with signs of lymphangitis - commonly seen in what bug?

A

pasteurella multocida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Erysipelas is often caused by ?

A

GAS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

MC bugs in acute diabetic foot infections?

A

S aureus
Streptococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Human bite mc infection?

A

polymicrobial - eikenella, fusobacterium, GAS, S aureus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cat bite common bug concern?

A

pasteurella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When do even dog bites need prophylactic abx?

A

face
hands
genitals
areas of poor perfusion
immunocomp pt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

First line treatment and bug: uncomplicated abscess

A

MRSA
I+D, abx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

First line treatment and bug: nonpurulent bacterial skin infection

A

strep, staph aureus
keflex or clinda, adjuncts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

First line treatment and bug: purulent cellulitis and wound infections

A

mrsa, strep
septra, doxy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

First line treatment and bug: DFU

A

mixed gram neg pos and anaerobes
amox clav and septra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

First line treatment and bug: cat bite or infected dog bite?

A

amox clav
pasteurella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

First line treatment and bug: human bite

A

oral anaerobes etc
amox clav

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

First line treatment and bug: erythema migranes

A

borrelia burgdoferi
doxy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

First line treatment and bug: puncture would through sole of shoe

A

pseudmonas
levo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
First line treatment and bug: buccal cellulitis
hinlfu ceftr or amp sulbactam
26
First line treatment and bug: balantis
candida albicans or GAS fluconazole and pen/amox + test for db
27
First line treatment and bug: Liposuction
peptostreptococcus, gas amp-clav acid and septra
28
First line treatment and bug: saltwater exposure
vibrio vulnificus doxy
29
First line treatment and bug: freshwater
aeromonas sp ciprofloxacin
30
First line treatment and bug: butcher, clam handler or vet
erysipelothrix rhusiopathiae amoxicillin
31
First line treatment and bug: black necrotic eschar with rasied border and severe edema?
bacillus anthracis (anthrax) cipro
32
Who is particularly at risk from vibrio of salt water?
liver disease pt
33
Pseudocellulitis ddx
venous stasis derm burns viral infection fixed drug eruption lymphedema VTE gout contact dermatitis
34
ALT-70 to differentiate cellulits from pseudo - what does this entail?
Asymm Leukocytosis tachycardia age >/=70
35
If necrotizing infection is thought ,what imaging can be helpful?
ct but should really call prs/service in charge
36
How long to tx bites for?
3-5d
37
Bite infection - pen allergic (severe) alternative?
clinadymin
38
What is an abscess?
bacteria multiplication below the epidermis
39
Carbuncle defn
multiple furuncles with loculation and connecting sinus, often mult sites of drainage
40
Furuncle defn
Boil - abscess of the hair follicle
41
Carbuncle place mc and disease RF?
neck diabetes
42
Bartholin gland cyst - what to test for?
STBBI
43
Pilonidal abscess - where is this?
superior aspect of gluteal cleft between buttocks --> surgical excision referral by surg
44
Concerning signs for necrotizing fasc?
1. systemic toxicity - pain out of proportion, abnormal vitals, AMS 2. crepitance 3. skip lesions/radid progression 4. hemorrhage, sloughing, blisterin
45
Ultrasound findings of an abscess
hypoechoic areas with posterior acoustic enhancement
46
Oral options for MRSA
clinda septra doxy linezolid
47
What is an epidermoid cyst?
benign cystic tymor for accumulation of kertainecous material -can be painful, rupt spontaneously -can tx abx and nsaid
48
How to I+D an abscess?
analgesia incise blunt dissect irrigate pack
49
How to tx a Bartholin Abscess?
small incision around 3mm on site, cavity drained word catheter insertion and inflated with 4ml of saline leave in place 4-6 weeks so sinus tract can form sitz bath
50
When to consider other tx for a barhtolin gland cyst?
marsupialization if recurrent (but no usually acute)
51
Abx post abscess?
simple, no risk mrsa - risk/benefit discussion with pt abx if limited f/u, assocv cellulitis, mult infection sites, systemic illness, assoc comribdities and immunosuppression, extreme of age, abscess in area difficult to drain (hands, genitalia, feet), septic phlebitis, poor response to I+D alone
52
Impetigo two forms?
bullous and non
53
What does impetigo look like?
thin walled vesicles progressing to pustules, honey crusted lesions on face or extremity often have lymphadenopathy
54
Bullous impetigo bug
S aureus, MRSA toxin procudes bullae from dermal epidermal junction release (0.5-3cm)
55
Deep impetigo - what does this look like?
ulcers, punched out appearance, rasied red margins covered. with thick crust typically LE
56
Nonbullous impetigo tx
topical mupirocin multiple lesions/extensive tx with MRSA
57
Bullous impetigo tx
abx against MRSA and strep keflex + septra
58
Folliculitis defn
superficial inflamm of hair follicle limited to epidermis
59
What does folliculitis look like?
small 2-5mm raised erythematous, painful, tender lesions typically itchy ex beard, hot tub
60
Folliculitis tx
if regular - topical mupirocin, avoid trigger if candida concern (immunocomp) - tx antifungals, r/o immunocomp hot tub (pseudomonas)- cproflox and antihist
61
Hidraenitis suppurativa - what is this?
acne inversa - painful usually in axilla or inner area aceniform disorder with follicular occlusion rather than infection of sweat glands
62
Hidradenitits suppurativa tx
incision of painful nondraining lesions for sx release systemic abx for symptomatic lesions and should cover mrsa LT immunomod, hormones and en bloc resection (derm vs PRS) pain control key
63
RF nec fasc
db vascular insuff immunosuppression penetrat taruma recent surg varicella inection IVDU burns childbirth
64
What bugs cause nec fasc?
MC poly: GAS s aureus enterococci enterobacteriaceae anaerobes: bacteriodes, clostridium
65
2 types of nec fasc
1: polymicrobial: aerobe and anaerobes 2. single organism: GAS, MRSA
66
"Gas gangrene" - medical term
clostridial myonecrosis
67
MC cause of traumatic myosistis/myonecrosis?
clos perfringins exotoxins causing shock --> IV hemolysis + DIC
68
Anaerobic streptococcal myositis: bug? general course?
peptostreptococus, or GAS or S aureus insidious but still resembles clostridial myonecrosis
69
Pyomyositis defn
deep abscess within striated m resulting from hematogenous spread of bacteria in setting of m injury -S Aureus
70
Phlegmasia cerulea dolens - what is this?
iliofemoralvein thrombosis - may look like nec fasc
71
Nec fasc tx
clinda pip tazo vanco surg asap
72
3 main types of toxic shock syndromes
-staph -strep -staphyloccla scalded skin syndrome
73
Stretococcal toxic shock syndrome: can occur in ?
prior healthy people
74
Invasive GAS: how do toxins work?
exotoxin A and B act as superAg and cause overactivation of T cells with massive release CK - flu likefirst, then septic shock
75
GAS toxic shock syndrome: complications
DIC renal failure ARDS
76
Streptococcal TSS: organism and toxin
GAS, pyogenic exotoxion
77
Streptococcal TSS: source
nec infection
78
Streptococcal TSS: rash
erythematous rash only in 10% oftne have signs of nec infection and exfoliation weeks later
79
Streptococcal TSS: mortality %
30-80
80
Streptococcal TSS: tx
resus op debridement
81
Staph TSS: toxin and organism
tss type 1: enterotoxin A, B, C staph aureus
82
Staph TSS: pt type
prior healthy
83
Staph TSS: source
nasal wound or packing tampon infection may also not be clear
84
Staph TSS: rash
initially diffuse erythroderma exfoliation after 1-2wk, mucosal hyperemia
85
Staph TSS: systemic illness findings compared to strep
similar: hypotension, shock: multiorgan failure more likely in GAS > staph
86
Staph TSS: tx
resus
87
Staph ScaledSS: bug and toxin?
staph aureus epidermolytic toxin A or B
88
Staph ScaledSS: pt?
infant
89
Staph ScaledSS: source
skin flora
90
Staph ScaledSS: rash
tender erythematous rash localized blister extensive exfoliation if have no abx to toxin mucosa spread
91
Staph ScaledSS: sx
fever, irritability ( as particularly infant)
92
Staph ScaledSS: mortality
<5%
93
Staph ScaledSS: tx
wound care hydration
94
Staph TSS: mortality %
<5
95
What toxin is most associated with Staph TSS in menstrual causes?
TSST-1
96
SSSS: where does toxin target?
act as proteases - target protein desmoglein 1 on stratum granulosum layer or epidemrus
97
Staph ScaledSS: nikolsky?
+
98
Trend of rash in RMS fever?
wrists and spreads everywhere including palsm and soles macular --> petechial and then dusky
99
Anthrax rash presentation
incubation 1 week --> vesicle ruptures leaing shallow based ulcer with raised border painless necrosis and escar, surrounding edema
100
Tularemia: from?
exposure to rodents, rabbits hairs
101
Tularemia: skin presentation and other sx?
flu like ulceroglandular form lesion itself is raised vs border only in anthrax
102
Cutaneous leishmaniasis lesions:
face - painless, ulcerative, dysfiguring papules - wory about myiasis botfly!
103
What type of skin rash in kids can lead to PSGN?
impetigo
104
How to treat eosinoophilic folliculitis?
isotretinoin
105
SSSS - key: spares what?
mucous membranes