12. Skin And Breast Flashcards
5 layers of epidermis
Stratum corneum= dead keratinising squamous
Stratum lucidem
Stratum granulosum = flattened squames produce keratin
Stratum spinosum = polygonal keratinocytes, sensory Merkel cells and antigen recognising Langerhan cells
Stratum basale = single stem layer
Melanocyte function
MSH and ACTH stimulates melanocyte formation from tyrosine and transport to keratinocytes.
What are epidermal adnexae?
Downgrowths of epidermis into dermis
(Dermal papillae = boundary)
Sebaceous glands produce sebaceous secretion to lubricate + waterproof fair
Eccrine = most common gland
Apocrine
Nails
Compacted keratin from nail matrix cells firmly attached except at distal
Hair
Hair arise from germinative epithelium within bulb and contains melanocytes for hair colour
Epidermis root sheath surrounded by collagenous follicle sheath. Erector pills muscle causes hair to stand
2 layer of dermis
Papillary dermis = few collagen fibres
Reticular dermis = rich collagen fibres
Subcutis structure
White adipose connective tissue and fibrovascular septa = provides insulation, food store and shock absorber
Meissner’s corpuscle bs Pacinian Corpuscle
M - Encapsulated unmyelinated nerve endings under dermal papillae, surrounded by Schwann cells = fine touch
P - Encapsulated sensory receptors in deep dermis. Membrane lamellar separated by fluid = vibration + pressure
Eyelid
Inner moist conjunctival surface of stratified columnar
Large Meibomian gland = modified sebaceous secretes lipid rich to reduce evaporation
Breast
Myoepithelial system of ducts and lobules around terminal duct in fibroadipose connective tissue.
Outer myoepithelial, inner columnar
Lactating breasts
Inner layer of secretory cells become vacoulated