12 - evaluation of glucose metabolism

Question 1

hypoglycemia

come back to this

Question 2

hyperglycemia

come back to this

Question 3

(blood glucose analysis)

1. fast for 12 hours to avoid postprandial hyperglycemia
2. separate serum/plasma from cells w/in 30 minutes of collection -> glycolysis or RBCs reduce glucose

Question 4

(urine glucose analysis)

1. glucose appears in urine when renal threshold reached

what is it in dogs and cats?

Answer 4

180 to 200 mg/dL

Question 5

(glucose tolerance test)

1. useful for detecting what?

Answer 5

1. decreased glucose tolerance in persistently hyperglycemic animals

Question 6

(serum insulin)

1. most useful in hypoglyemic animals
2. collect insulin when?
3. what does it mean if insulin conc in middle part of reference range or above?

Answer 6

2. when glucose conc below 60 mg/dL
3. insulinoma suspected

Question 7

(fructosamine)

1. what does it measure?
2. affected by what?

Answer 7

1. blood glucose levels over last 5 to 8 days
2. protein level (hypo decreases and vice versa)

Question 8

(glycated hemoglobin)

1. reflects blood glucose over what span?
2. what will falsely decrease?

Answer 8

1. lifespan of RBC

8-12 wks in dogs

5-6 wks in cats

2. anemia