12 - Dermatology 1: Skin infections Flashcards
What are the layers of the skin?
- epidermis
- dermis
- hypodermis (SC fat)
What is the function of the skin?
- provide anatomical barrier
- main method of heat regulation
- sensory input
- storage for lipids and water
- drug absorption
- waste excretion
What are commensal flora?
- normal colonisation that prevent pathogens in healthy hosts
- mainly bacteria and fungi on skin (staphylococci and candida)
What is oily skin?
- increased secretion form sebaceous glands
- more bacterial colonisation
- skin becomes heavier and thicker
- more risk of pore blockage = more spots
- less likely to wrinkle and age
What is a comedone?
- blackhead
- build up of keratin and sebum
- blocked pores oxidise which gives black appearance
- is a feature of acne vulgaris
What are examples of bacterial infections of the skin?
- furuncles
- carbuncles
- acne
- erysipelas
- impetigo
What are furuncles?
- infection of skin that presents with pockets filled with pus
- caused by s aureus
- red, painful and swollen
- should be drained, do not require antibiotics
What are carbuncles?
Furuncles that are grouped together
What is folliculitis?
Furuncle in a hair follicle
What is acne?
Lesions arising from
- comedones
- papules
- pustules
- nodules
- inflammatory cysts
Who is most affected by acne?
Teenagers aged 13-18 (80% experience)
What are the causes of acne?
- follicular sensitivity to testosterone (increases during puberty)
- propionibacterium acnes overgrows and leads to infection
- scars can form if cysts rupture
What makes acne worse?
- contraceptive pills (containing progesterone)
- greasy skin cleansers
- systemic steroids
- anticonvulsant drugs
- squeezing spots
What is used as local management of acne?
- reduce excess skin oil (gentle soap cleansers)
- antibacterial agents (benzoyl peroxide, retinoids, antibiotic lotions)
What is sued as systemic management of acne?
- antibiotics (tetracycline based)
- retinoids (isotretinion)
- hormone manipulation (anti-androgens)
What is erysipelas?
- presents with defined raised order, may blister and peel
- systemic symptoms include fever and shivering
- caused by streptococcus pyogenes
- can progress to necrotising fasciitis or septic shock
How do you manage erysipelas?
Systemic antibiotics (oral or IV)
What is impetigo?
- highly infectious skin disease caused by staphylococcal or streptococcal bacteria
- presents with crusty red blister appearance
- associated with eczema