12/8/16 Mesolimbic Flashcards
What are three things the mesolimbic and PFC are activated by?
- Receiving reward
- Loved one
- Preferred brand
What is the Dopamine reward system?
-Mesolimbic
If you choose the immediate reward what system is the major controller?
-Mesolimbic
If you choose the delayed reward what is the major controller?
-Frontal cortex
In the mesolimbic system where is the first nucleus found?
-Ventral Tegmental Area
From is the nucleus from the ventral tegmental area?
-Nucleus accumbens
From the VTA what is the next place we go?
-Pre-frontal cortex
Where do you find the VTA?
-By the substantia Nigra
Where does the Dopamine from the VPA go?
-Nucleus accumbens
When you send out dopamine from the VPA what else do you send out?
-An inhibition to the Pre frontal cortex
Alcohol, Nicotine, Opiods, Cocaine modify what structures function?
-VTA
Drugs of addiction affect the function of what structure?
-VTA
Where is the Nucleus accumbens located?
-Head of the caudate and the anterior portion of the putamen
What is the linking function of the nucleus accumbens?
-Link emotions, planning and motivation
What happens if you damage the nucleus accumbens?
- Induce hyperactivity
- Impulsivity
T/F
The nucleus accumbens involve using GABA and acetylocholine
True
Where do you need lots of inhibition to stop the impulsivity?
- Dorsal striatum
- Globus pallidus
What connects the VTA and the nucleus accumbens?
-Medial forebrain bundle
What does the pre-frontal cortex connect to and have to interact with?
Dorsal-medial thalamus
What nucleus from the PFC deals with memory and situation context? (Remember you had a good time doing something)
-Ventrolateral PFC
What nucleus from the PFC deals with Apathy and Faux Pas (something terrible you’ve done)?
-Orbital (basal) PFC
What part of the PFC is responsible for executive function?
-Dorsolateral PFC
What part of the PFC is integrated with Motor function?
-Dorsolateral PFC
What is a term that deals with the divisions in the PFC?
-Cytoarchitectonics
T/F
Internal stimulation is fast response and external stimuli are slow response
True
When you think its all about me what stimuli is dominant?
-Internal stimuli (default network)
When you forget about yourself what is the stimuli responsible?
-Attention network (external stimuli)
