12/2/16 Limbic System Flashcards
What structure in the brain is responsible for fear?
-Amygdala
What structure in the brain is responsible for memory?
-Hippocampus
T/F
The hippocampus helps with spacial recognition of where you are at.
True
In the limbic system where do you go from the hypothalamus?
-Anterior thalamus
In the limbic system where do you go from the anterior thalamus?
-Cingulate cortex
In the limbic system where do you go from the cingulate cortex?
-Hippocampus
In the limbic system where do you go from the hippocampus?
-Hypothalamus
What two responses do you get from the limbic system?
- Feeling
- Bodily response
What takes in information from all over the cortex in the circuit of papez?
-Cingulate gyrus
What does information travel through from the cingulate gyrus to the parhippocampal gyrus?
-Cingulum
When information travels from the cingulate gyrus through the cingulum where does it go?
-Parahippocampal Gyrus
What does information travel through from the parahippocmpal gyrus to the hippocampus?
-Perforant Path
When information travels from the parahippocampal gyrus through the perforant path where does it go?
-Hippocampus
What does information travel through from the hippocampus to the mammillary bodies?
-Fornix
When information travels from the hippocampus through the fornix where does it go?
-Mammillary bodies
What does information travel through from the mammillary bodies to the anterior thalamus?
-Mammillo-thalamic tract
When information travels from the mammillary bodies through the mammillo-thalamic tract where does it go?
-Anterior thalamus
What does information travel through from the anterior thalamus to the cingulate gyrus?
-Thalamo-cortical tract
When information travles from the anterior thalamus through the thalamo-cortical tract where does it go?
-Cingulate gyrus
T/F
Wernicke-Korsakoff Syndrome is a type of Limbic Amnesia
True
What is the major cause of Wernicke-Korsakoff syndrome?
-Vitamin B1 deficiency & alcoholism
What is the site of wernicke-korsakoff syndrome?
-Mammilo-thalamic tract disrtuption
What are the symptoms of Wernicke-Korsakoff Syndrome?
- Inability to form new memories
- Loss of memory
- Hallucinations
- Confabulation
Do you confabulate in Wernicke’s syndrome?
-No
What are the three functions of the hippocampus?
- Memory consolidation
- Motivation
- Location
What are the three major divisions of the hippocampus?
- Dentate gyrus
- CA3 (cornus Ammon 3)
- CA1 (Cornus Ammon 1)
T/F
The dentate nucleus has ongoing cell division throughout your life
True
What is the major afferent of the hippocampus?
-Perforant Path
What is the Intrinsic (Trisynaptic circuit)?
-The pathway from the Dentate gyrus, CA3, and CA1
What is the major efferent of the hippocampus?
-Fornix
What is the minor afferent to the hippocampus?
Fornix
What is the first step of the trisynaptic circuit?
-From the entorhinal cortex through the perforant pathway to the dentate gyrus
What is the second step of the trisynaptic circuit?
-From the dentate gyrus through the mossy fibers to the hippocampus (CA3)
What is the third step of the trisynaptic circuit?
-From CA3 through schaffer collaterals to CA1
What are the two parts of the fornix that branch off?
- Post commissural (circuit of papez)
- Pre commissural (resent through the pathway)
When you have damage to the medial temporal lobe what is a common disease?
-Limbic Amnesia
T/F
Amnesia has to be bilateral medial temporal lobe damage
True
When you have damage to the hippocampus what are the signs?
- Cannot form new memories
- Can recall prior events
What does Alzheimers damage?
-Bilateral Hippocampus damage
What are four common alzheimer’s deficits?
- Amnestic
- Reduced motivation
- Trouble navigating familiar places
- General Cognitive Impairment
What are the three major anatomical divisions of the amygdala?
- Basolateral complex
- Corticomedial
- Central nucleus
What does the corticomedial division of the amygdala deal with?
-Olfactory
What does the central nucleus of the amygdala deal with?
-Autonomic
What are the two major efferents that come from the amygdala?
- Amygdalofugal
- Stria terminalis
Where in the amygdala does the stria terminalis come from?
-Central nucleus
When you bang a book what makes you jump?
-The pathway through the ventral amygdalofugal fibers
When you bang a book what pathway makes you want to run?
-The pathway through the stria terminalis
When patients have amygdala damage what might you see?
- Poor conditioned emotional response
- Poor recognition of fear, especially facial recognition
What is the cause of Kluver-Bucy syndrome?
-Bilateral lesions to the amygdala caused by Trauma, Tumors, or Viral
What are the symptoms of Kluver bucy syndrome
- Docility
- Overeating
- Hyperphagia
- Hyperorality
- Hypersexuality
- Visual agnosia
