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Microbio > 12/4 Quiz Pathogenicity > Flashcards

12/4 Quiz Pathogenicity Flashcards

1
Q

refers to a microbe’s ability to cause a disease

A

Microbial Pathogenicity (P)

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2
Q

P=NV/R

A

P=Pathogenicity
N = number
V = virulence
R = resistance

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3
Q

the greater the number of invading microbes,

A

the greater the chance that the microbe will overcome the host defenses

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4
Q

Host Resistance depends upon

A

innate 1st and 2nd lines of defense and a specific 3rd line of defense
(immune response)

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5
Q

the properties of a microbe that enhance pathogeniity

there are degrees of pathogenicity

A

Virulence

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6
Q

the microbe’s ability to to replicate rapidly

A

Invasiveness

Virulence

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7
Q

how well a microbe attaches to the host

  • fimbriae? spikes? glycocalyx?
  • are somewhat specific
A

Invasiveness

Virulence

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8
Q
  • Enzymes

- Adapting/Utilizing vector to penetrate 1st line of defense

A

Promote Microbial Entry to Host Tissues
Invasiveness
Virulence

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9
Q

Produced by some fungi and digests the keratin in skin

A

Keratinase
Microbial Entry to Host Tissues
Invasiveness
Virulence

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10
Q

digests hyaluronic acid, intercellular “cementing” substance between surface cells

A

hyaluronidase
Microbial Entry to Host Tissues
Invasiveness
Virulence

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11
Q

enzyme that digests collagen, most common protein/CT in the body

A

Collagenase
Microbial Entry to Host Tissues
Invasiveness
Virulence

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12
Q

convert plasminogen into plasmin, an enzyme that breaks down blood clots

A

Streptokinase/Staphylokinase
Microbial Entry to Host Tissues
Invasiveness
Virulence

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13
Q

causes a web-like clot that impedes WBC movement

A

Coagulase
Microbial Inhibition of Phagocytosis
Invasiveness
Virulence

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14
Q

kills WBC

A

Leukocidin
Microbial Inhibition of Phagocytosis
Invasiveness
Virulence

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15
Q

mechanically interfere with phagocytosis

A

Fimbriae and Capsules
Microbial Inhibition of Phagocytosis
Invasiveness
Virulence

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16
Q

resistant cell walls may inhibit digestion by phagocytes

A

Fact.

17
Q

bacterial are toxins that act as pores

  • lyse red blood cells
  • iron released from RBC’s appropriate for microbial use
  • ALPHA’s cause partial hemolysis, leaving greenish ring around microbial colonies
  • BETA’s cause complete hemolysis, leaving clear ring around micorbial colonies
A

Hemolysins
Acquisition of Host Resources
Invasiveness
Virulence

18
Q

Viruses enter host cells and take over the resources and machinery of their hosts

A

Acquisition of Host Resources
Invasiveness
Virulence

19
Q

Toxins disrupt the cell membrane or the internal activities of a cell

A

Toxigenicity

20
Q

-are the lipid A part of te outer membrane of Gram-NEGATIVE bacteria

A

Endotoxins

Toxigenicity

21
Q

-are relased when G- bacteria die

A

Endotoxins - Lipid A

Toxigenicity

22
Q

are weak, nonspecific and CAUSE A FEVER

A

Endotoxins - Lipid A

Toxigenicity

23
Q

Stimulate weak immunity

A

Endotoxins - Lipid A

Toxigenicity

24
Q

Stable

  • can’t be denatured and converted into toxoid
  • can’t be used for immunizations
A

Endotoxins - Lipid A

Toxigenicity

25
Q

associated with a few Gram+ and few G- bacteria

A

Exotoxins

Toxigenicity

26
Q

are secreted

A

Exotoxins

Toxigenicity

27
Q

polypeptide, unstable, powerful, do NOT tend to cause fever

A

Exotoxins

Toxigenicity

28
Q

can be denatured and converted to TOXOID whhich can be used for immunization

A

Exotoxins

Toxigenicity

29
Q

are highly specific

A

Exotoxins

Toxigenicity

30
Q

attack the nervous system

A

Exotoxins - NEUROTOXINS

Toxigenicity

31
Q

attack organs of the digestive tract

A

Exotoxins - ENTEROTOXINS

Toxigenicity

Microbio (14 decks)

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