1.1Common Teratogens and Effect Flashcards

1
Q

ACE inhibitors

A

fetal renal damage

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2
Q

antiepileptic druygs

A

neural tube defects

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3
Q

phenytoin

A

fetal hydantoin syndrome

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4
Q

oral hypoglycemic agents

A

neonatal hypoglycemia

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5
Q

barbiturates

A

neonatal dependence

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6
Q

DES

A

vaginal cancer

adenocarcinoma

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7
Q

ethanol

A

fetal alcohol syndrome

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8
Q

lithium

A

ebstein’s anomaly

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9
Q

craniofacial malformations

A

isotretinoin

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10
Q

iodide

A

congenital hypothyroidism

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11
Q

misoprostol

A

mobius sequence

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12
Q

penicillamine

A

cutis laxa

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13
Q

thalidome

A

phocomelia

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14
Q

smoking

A

IUGR

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15
Q

tetracycline

A

tooth discoloration

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16
Q

streptomyci

A

ototoxicity

17
Q

methimazole

A

aplasia cutis congenita

18
Q

sulfonamides

A

kernicterus

19
Q

fluoroquinolone

A

cartilage damage

20
Q

warfarin

A

first trimester : chondrodysplasia
second: CNS malformations
3rd : bleeding diathesis