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Muscular and Skeletal Systems > 11.2 Skeletal Muscle Part 2 > Flashcards

11.2 Skeletal Muscle Part 2 Flashcards

1
Q

What is the I band?

A

portion of the sarcomere that is solely composed of thin filament

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2
Q

What is the A band?

A

full length of thick filaments

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3
Q

What is the H zone?

A

thick filament only region of the sarcomere

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4
Q

Where are contractions generated in muscle cells?

A

overlapping region of thick and thin filaments

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5
Q

What powers filament sliding?

A

ATP hydrolysis

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6
Q

What is the function of the myosin head?

A

attaches to a specific site on an actin molecule called the myosin binding site

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7
Q

What is a cross bridge?

A

when actin and myosin are attached

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8
Q

What are the four steps of filament sliding?

A
  1. binding of myosin head to actin
  2. power stroke
  3. binding of a new ATP molecule releasing actin from myosin head
  4. ATP hydrolysis causes myosin head to cock
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9
Q

In the myofiber when does contraction occur?

A

when calcium concentration in cytoplasm increases

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10
Q

What is the function of the troponin-tropomyosin complex?

A

prevents contraction when calcium is not present

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11
Q

What is troponin?

A

globular protein bound to tropomyosin that can bind calcium

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12
Q

What is tropomyosin?

A

long fibrous protein that winds around actin polymer blocking all myosin binding sites

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13
Q

What occurs when troponin binds calcium?

A

troponin undergoes a conformational change moving tropomyosin out of the way so myosin head can attach to actin

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14
Q

What is the neuromuscular junction?

A

synapse between an axon terminus and a myofiber

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15
Q

What is the motor end plate?

A

postsynaptic membrane (myofiber cell membrane)

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16
Q

What is the neurotransmitter found at the neuromuscular junction?

A

acetylcholine

17
Q

What is the end plate potential?

A

depolarization of postsynaptic membrane caused by an influx of sodium

18
Q

What is a miniature end plate potential?

A

smallest measurable EPP caused by exocytosis of a single ACh vesicle

19
Q

What is acetylcholinesterase and what is its function?

A

enzyme that destroys ACh by hydrolyzing it into a choline and acetyl unit

20
Q

What are transverse tubules?

A

deep invaginations in myofiber allowing action potentials to travel through the thick cell

21
Q
A

Muscular and Skeletal Systems (12 decks)

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