11.1 and 11.2 Flashcards
Gene regulation
The turning on and off of genes within a cell in response to environmental stimuli or other factors (such as developmental stage)
Gene expression
The process whereby genetic information flows from genes to proteins; the flow of genetic information from the genotype to the phenotype
Promoter
A specific nucleotide sequence in DNA located near the start of a gene that is the binding site for RNA polymerase and the place where transcription begins
Operator
In prokaryotic DNA, a sequence of nucleotides near the start of an operan to which and active repressor protein can attach. The binding of repressor presents the RNA polymerase from attaching to the promoter and transcribing the genes of the operon. The operator sequence thereby acts as a genetic switch that can find all the genes in an operon on or off as a single functional unit
Operon
A unit of genetic regulation common in prokaryotes; a cluster of genes with related functions, along with the promoter and operator that control their transcription
Repressor
A protein that blocks the transcription of gene or operon
Regulatory gene
A gene that codes for a protein, such as a repressor, that controls the transcription of another gene or group of genes
Activators
A protein that switches on a gene or group of genes
Differentiation
The specialization in the structure and function of cells that occurs during the development of an organism; results from selective activation and deactivation of the cells genes
Histone
A small protein molecule important in DNA packing in the eukaryotic chromosome. Eukaryotic chromatin consists of roughly equal parts of DNA and histone protein
Nucleosome
The bead like unit of DNA packing in a eukaryotic cell; consists of DNA wound twice around a protein core made up of eight histone molecules
Epigenetic inheritance
The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence of a genome, such as the chemical modification of histone proteins or DNA bases
X chromosome inactivation
In female mammals, the inactivation of one X chromosome in each somatic cell
Barr body
A dense body formed from a deactivated X chromosome found in the nuclei of female mammalian cells