11. 1 Lactation Flashcards
What blocks breast development in males?
Testosterone
What is mammogenesis?
Preparation of breasts during pregnancy
What happens in mammogenesis?
Hypertrophy of the ductular-lobular-alveolar system
Prominent lobules form
Alveolar cells differentiate
Why is milk not secreted in mid-gestation?
Oestrogen to progesterone ratio high
What effect does progesterone have on the breast?
Inhibits prolactin receptors
What does oestrogen stimulate in the breast?
Angiogenesis in the breast surface
How do Montgomery tubules form?
Sebaceous glands fuse with the areola ducts
What do Montgomery tubules secrete?
Oils
Pharamones
What is the milk in days 0-3 after birth called?
Colostrum
What is colostrum made of?
More protein than normal milk
IgA to coat intestinal mucosa
Where is prolactin released from?
Anterior pituitary
What is released from the hypothalamus to stimulate dopamine release?
Dopamine
What is the stimulus for prolactin release?
Baby suckling
What is galactokinesis?
Ejection of milk
Which hormone is involved in the contraction of the acini to eject milk?
Oxytocin
