10. Ventricular Function Flashcards
1
Q
SV=
A
EDV-ESV
2
Q
CO=
A
HR x SV
3
Q
LaPlace’s Law -
A
- The larger the radius of a
chamber, the larger the wall tension required
to withstand a given internal fluid pressure.
4
Q
SW=
A
MAP x SV
5
Q
determinants of EDV
A
Preload
6
Q
determinants of ESV
A
Afterload, inotropic state
7
Q
Cardiac Glycosides
A
inhibit na/k pump
eg. digoxin
8
Q
Adrenergic agonist
A
increase Ca++
Increase inotropic state
9
Q
Cholinerginc agonist
A
decrease Ca++
decrease inotropic state
10
Q
Factors influencing inotropic state
A
Action potential changes (duration) Exernal ion conc( ca and na) Frequency neurotransmitters (agonists) Hormones/ drugs ( cardiac glycosides) Calcium blockers Ischaemia/ heart failure
11
Q
factors affecting preload
A
blood volume
venous tone
12
Q
factors affecting afterload
A
systemic pressure (hypertension) aortic stenosis
13
Q
max. rate of rise of ventricular pressure can be used as?
A
indicator of contractility
