10 - Drugs And The Nervous System Flashcards
The nervous system allows an organism to…
Sense and respond to the environment
The peripheral nervous system (PNS) comprises the… (2)
Afferent and efferent systems (input and output)
Efferent (output) system of PNS can be divided into two branches…
Autonomic and somatic
Autonomic nervous system is divided into…
Sympathetic (fight or flight) and parasympathetic (rest and digest) branches
The somatic nervous system provides the motor innervation of…
Skeletal muscles
The autonomic nervous system is involuntary and controls…
Smooth muscle
Neurotransmitters of the sympathetic nervous system (excluding sweat glands and adrenal glands)…
Pre-ganglion = Ach Post-ganglion = Noradrenaline
Neurotransmitters for sweat glands are…
Pre-ganglion = Ach Post-ganglion = Ach
Neurotransmitters for adrenal glands…
Pre-ganglion = Ach
Adrenal medulla = Adrenaline
The neurotransmitter of the parasympathetic nervous system…
Both pre and post ganglion use acetylcholine
In the somatic efferent nervous system (e.g. skeletal muscle), the neurotransmitter released across the NMJ is…
Acetylcholine
Acetylcholine is synthesised from choline by…
Choline acetyl transferase (CAT) 😺
Acetylcholine is bound by either…
Muscarinic or nicotinic receptors
Acetylcholine is broken down at the synapse by the enzyme…
Acetylcholine esterase (AchE)
Muscarinic Ach is found at…
Post-ganglionic parasympathetic synapses
