08 - General principles of drug action Flashcards
1
Q
In the one compartment model, drugs are considered to be…
A
Absorbed and distributed immediately throughout the body
2
Q
Most drugs follow which order of kinetics?
A
First order kinetics
3
Q
In first order kinetics the rate limiting factor is…
A
Concentration of drug
I.e. rate of decrease slows down as concentration decreases
4
Q
Zero order kinetics occurs when the drug is present…
A
At saturation
5
Q
In zero order kinetics, the decrease in drug is…
A
Independent of plasma concentration
6
Q
In the two compartment model, the body is divided into (2)…
A
Peripheral compartment (slow) and central compartment (fast)
