10/1 Questions Flashcards

1
Q

What compensates for the thinness of the posterior part of the cervical annulus fibrosus?

A

posterior longitudinal ligament

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2
Q

What is the organization of the lumbar annulus fibrosus?

A

it has 12-14 concentric cylindrical lamellae

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3
Q

Why is the posterior part of the lumbar annulus fibrosus more susceptible to rupture, herniation, prolapse, or protrusion?

A

the posterior margin of each lamellus is thin and the posterior longitudinal ligament is also less developed

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4
Q

What is the water concentration in the lumbar annulus fibrosus at birth and after thirty?

A

birth - 78%

thirty - 70%

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5
Q

What is the organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus?

A

they typically have a binding site for hyaluronic acid and are thus aggregated

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6
Q

Which type of collagen is dominant in the annulus fibrosus?

A

collagen type 1

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7
Q

What is the organization pattern for collagen fibers in the annulus fibrosus?

A

they are parallel with one another in a single lamellus and angled

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8
Q

What is the organization of collagen fibers between lamellae?

A

collagen fibers will be angled in the opposite direction such that a spiral - counterspiral organization is observed

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9
Q

What is the average angle of collagen fibers within the annulus fibrosus?

A

they average 50 to 60 degrees

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10
Q

What is the attachment site for collagen fibers within the annulus fibrosus?

A

collagen fibers of the outer lamellae will become sharpey’s fibers and penetrate the epiphyseal rims; collagen fibers of the inner lamellae will attach to the cartilaginous end plate

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11
Q

What is the origin for the cells of the annulus fibrosus?

A

sclerotomites

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12
Q

What cell type is associated with the annulus fibrosus?

A

fibroblast and fibrocyte

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13
Q

What is the cartilage end plate derived from?

A

the epiphyseal plate

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14
Q

What is the thinnest part of the cartilage end plate?

A

the central part, over the nucleus pulposus

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15
Q

What part of the vertebral body will the cartilage end plate cover?

A

the cancellous bone at the top or bottom of the vertebral body

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16
Q

What part of the vertebral body upper and lower surfaces will the cartilage end plate not cover?

A

the epiphyseal rim

17
Q

What is the principal type of collagen fiber within the cartilage end plate?

A

the type II collagen fiber

18
Q

What is the direction of collagen fibers within the cartilage end plate?

A

collagen fibers are aligned anterior to posterior

19
Q

What is the attachment site for collagen fibers of the inner lamellae of the annulus fibrosus?

A

the cartilaginous end plate

20
Q

What cell type is associated with the cartilage end plate?

A

chondrocytes

21
Q

What is the earliest indicator of intervertebral disc pathology or degeneration?

A

changes in the histology of the cartilage end plate

22
Q

What is the appearance of the cervical annulus fibrosus?

A

a horse-shoe with the anterior margin thick and the lateral margins tapering to the uncinate processes; the posterior margin is thin