1- population health Flashcards
the fundamental theorem of natural selection
rate of adaptation/improvement is proportional to strength of selection + amount of variation
primary genetic risk to a breed is:
loss of genetic diversity
what happens if you stop breeding carriers?
-creates bottleneck effect and decreases genetic diversity
-this may cause increase drift of other disorders
rules of breeders/genetic testing
- avoid selection for extreme phenotypes
- use genetic testing to select healthy breeding animals
- be willing to modify breeding practices
3 ways to reduce disease allele prevalence
- genetic testing of parents
- phenotypic testing of parents
- pedigree analysis
what to do when you have simple autosomal recessive disorder with genetic test
breed with quality carriers to normal testing individuals
why are linkage markers used for autosomal recessive disorders
to make sure its not a recombination event
avoid _____ but don’t necessarily avoid some __________
inbreeding
line breeding (breeding relatives with a lower coefficient of relatedness)
a population with no _____ cannot respond to selection
variation
some examples of stakeholders in the genetic health of domestic animals
pet owners, breeders, registries, vets, geneticists
genetic testing should be used to determine _________________ and not ___________.
who to mate an individual to
whether to mate an individual