1. Parentage control, DNA-allelic polymorphisms Flashcards
Which method is used for parentage control in domestic animals?
Analysis of SNPs (point mutations)
Only by detection of blood groups
Analysis of co-dominantly inherited and polymorphic microsatellites based on exclusion
Detection of polymorphic enzymes
Analysis of co-dominantly inherited and polymorphic microsatellites based on exclusion
How can be controlled an alleged paternity?
Detection of monomorphic alleles inherited on Y-chromosome
Detection of inherited polymorphic alleles based on exclusion
It is possible only with detecting of monomorphic gene loci
Detection of X- and Y-chromosome-specific and not polymorphic sequences
Detection of inherited polymorphic alleles based on exclusion
How are blood groups inherited?
All the blood groups show a recessive mode of inheritance
Co-dominantly
Dominantly but their penetrance and expressivity may change
Recessively but may show varying expressivity
Co-dominantly
Which are the most frequently used polymorphic DNA sequences in parentage control?
SNPs
RFLPs
Only the coding and less polymorphic DNA sequences
Highly polymorphic and non coding DNA sequences (microsatellites, STRs, VNTRs)
Highly polymorphic and non coding DNA sequences (microsatellites, STRs, VNTRs)
How can the blood groups be detected?
With poliacrylamid gel electrophoresis (PAGE)
With laboratory immunological test
PCR method
Only with molecular genetics method
With laboratory immunological test
What are blood groups in domestic animals?
Immunoglobulins (antibodies) which make haemolysis or agglutination of red blood cells
Both antigens and antibodies are called as blood group
Enzymes on the surface of the red blood cells
Genetically determined antigen set on the surface of the red blood cells inherited from parents
Genetically determined antigen set on the surface of the red blood cells inherited from parents
What are microsatellites?
Sequences which become polymorphic based on point mutation
Polymorphic DNA sequences cut by restriction endonucleases
Non coding DNA sequences which are polymorphic on the base of repeating numbers of DNA units
The latest name of macrosatellites
Non coding DNA sequences which are polymorphic on the base of repeating numbers of DNA units
What is genetic or genotype polymorphism?
On the same locus there are only two allelic variants at population level
On the same locus there are two or more allelic variants at population level
The gene loci show monomorphism
The configuration and conformation of gene products (proteins , enzymes) are identical
On the same locus there are two or more allelic variants at population level
Which types of immunoglobulins are used to detect blood groups?
Only IgA and IgM antibodies
Mixture of polymorphic antibodies
Mixed antibodies
Blood group specific antibodies
Blood group specific antibodies
What are blood group systems?
The total of blood groups in the same species
Only the monomorphic blood group antigens
Linkage group of antigens in a coding region on the same chromosome
The polymorphism of blood groups
Linkage group of antigens in a coding region on the same chromosome
