1. Overview (Lecture) Flashcards

1
Q

It is the study of immunity

The ways in which the immune system can be advantageously manipulated to protect against or treat diseases

More of concept

A

Immunology

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2
Q

The ability of an organisms to resist infections or disease

A

Immunity

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3
Q

The study of the fluid components of the blood especially antibodies

More of application

A

Serology

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4
Q

Most frequently encountered specimen in immunologic testing

A

Serum

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5
Q

NOTE: Serum is used to identify antigen and antibodies

A
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6
Q

Differentiate the recognize self from non-self

A

Immuno tolerance

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7
Q

Natural resistance, recovery and acquired resistance to infectious diseases

A

Desirable effects of IRs

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8
Q

Hypersensitivity, allograft rejection, autoimmune diseases

A

Undesirable effects of IRs

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9
Q

NOTE: Non-Self materials range from infectious microorganisms to life-saving organ transplantation

A
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10
Q

Describes a plague in Athens during the Peloponnesian war

Meaning: Those who recovered from the plague could nurse the sick without being infected

A

Thucydides (430 BC)

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11
Q

What year chinese developed a custom of inhaling crusts from smallpox lesions to prevent the development of smallpox later in life

A

1500 AD

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12
Q

Causative agent of smallpox?

A

Variola virus

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13
Q

Introduced the practice of Variolation to western medicine

A

Lady Mary Wortley Montagu 1718

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14
Q

NOTE: Smallpox Contains Virulent Virus

A
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15
Q

Injecting materials from smallpox blisters; widely practiced in eastern medicine

A

Variolation

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16
Q

Variolation came from Infected person meaning, it contains virulent virus

A
17
Q

Considered the father of immunology

Who discovered the smallpox vaccine

A

Edward Jenner 1798

18
Q

NOTE: Edward Jenner He noticed that milkmaids who contracted cowpox were spared from smallpox epidemics

This then inoculated to a boy to inject cowpox blisters which provides immunity to smallpox

A
19
Q

Vaccination came from the word Vacca meaning?

A

Cow

20
Q

Immunity developed from one disease will also be effective to another

Ex. Cowpox and smallpox

A

Cross immunity

21
Q

Father of modern microbiology

Discovered attenuated (Weakened or killed) vaccines

Discovered vaccines against rabies, Anthrax, and chicken cholera

(Can be considered as the father of immunology)

A

Louis Pasteur

22
Q

Causative agent of chicken pox?

A

Varicella zoster virus

23
Q

The ability to triggered immune responce

A

Immunogenicity

24
Q

Cellular theory f immunity through phagocytsis

Experimented on starfish larvae

A

Elie Metchnikoff (1880-1900)

25
Q

Factors that are dissolved in the blood (Soluble factors)

A

Humoral factors

26
Q

NOTE: The theory of phagocytosis is not well accepted because of humoral factors not until Opsonins was discovered

A
27
Q

Antigen-antibody binding is also known as?

A

Lattice hypothesis

28
Q

glycoproteins produced by the immune system in response to exposure from an immunogenic material

Hallmark of immunogenic material

A

Antibody

29
Q

Antibody is also known as?

A

Immunoglobulin or gamma globulin

30
Q

Any material that is capable of binding to the product of an immuno response

A

Antigen

31
Q

Any material that is capable of eliciting an immune response in an immunocompetent host

A

Immunogen

32
Q

NOTE: ALL immunogens are Antigens

A
33
Q

NOTE: Not ALL antigens are immunogens

A
34
Q

The reaction of the immune system to immunogenic stimulation

A

Immune response

35
Q

A form of immune defense represented by antiodies and other soluble factors in the blood and body fluids

A

Humoral immunity

36
Q

A form of immune defense represented by immune cells such as lymphocytes, phagocytic cells, antigen-presenting cells and inflammatory cells.

A

Cell mediated immunity

37
Q

Basis for the vaccination wherein the pathogens became less virulent, can be weaken or be killed

A

Attenuation

38
Q

Where did Eli Metchnikoff observe phagocytosis?

A

Starfish Larvae