1 Endocrine System Flashcards

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1
Q

what is paracrine communication?

A

products of secretion affects neighbouring cells

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2
Q

what is exocrine secretion?

A

products of secretion released into a body cavity

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3
Q

what is the main feature of endocrine glands?

A

ductless glands

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4
Q

what forms can hormones come in?

A

proteins, polypeptides or lipids

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5
Q

what examples of hormones are at constant levels?

A

thyroid hormones

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6
Q

what is an example of a hormone that is at a variable level?

A

hormones such as epinephrine

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7
Q

what is an example of a cyclic level hormone?

A

reproductive hormones

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8
Q

what are amine hormones?

A

derivatives of the amino acid tyrosine

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9
Q

what are examples of amine hormones?

A

dopamine, T3 or T4

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10
Q

what are peptide hormones?

A

the majority of hormones, may also serve as neurotransmitters

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11
Q

what are steroid hormones?

A

produced by the adrenal cortex and the gonads

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12
Q

what are examples of steroid hormones?

A

cortisol or oestrogen

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13
Q

how can hormones travel in the blood?

A

water soluble hormones travel dissolved in plasma, there circulate in the blood bound to plasma proteins

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14
Q

how are hormones broken down?

A

either excreted by kidneys or metabolised in blood or target cells

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15
Q

what is up regulation?

A

a low concentration of a hormone is compensated for by an increase in number of receptors

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16
Q

what is down regulation?

A

a high concentration of hormone compensated for by a reduction in number of receptors

17
Q

what is antagonism?

A

a hormone reducing the number of receptors available for a second hormone resulting in decreased effectiveness of the second hormone

18
Q

what is permissiveness?

A

a hormone increasing receptors available for second hormone making it more effective

19
Q

what are catechalomines?

A

hormones made by the adrenal gland

20
Q

where are receptors for peptide hormones and catecholamines found?

A

on extracellular surface of plasma membranes

21
Q

where are receptors for steroid and thyroid hormones found?

A

mainly on intracellular surface of the membrane or nucleus due to being lipid soluble

22
Q

what action can a hormone binding to a receptor have?

A

open ion channels, enzyme activity, activity of kinases, turn on genes for second messengers

23
Q

what does the anterior pituitary control?

A

functions of endocrine glands

24
Q

what are the 5 main cell types of the anterior pituitary?

A

gonadotroph, lactotroph, somatotropin, corticotroph, thyrotroph

25
Q

what do gonadotrophs secrete?

A

LH, FSH

26
Q

what do somatotropin secrete?

A

somatostatin and growth hormone

27
Q

what do corticotrophs secrete?

A

ACHT

28
Q

what do thyrotrophs secrete?

A

thyroid stimulating hormone

29
Q

what hormones are secreted by anterior in response to hypothalamus?

A

ACTH, TSH, GH, PRL, FSH and LH

30
Q

what hormones are stored in the posterior?

A

MSH, Oxytocin and ADH

31
Q

what is the difference between the anterior and posterior pituitary?

A

anterior is under control via hypothalamus, yet posterior carries out direct release of hormones

32
Q

how does negative feedback occur in hypothalamus control?

A

the tissue targeted by the pituitary produces a hormone that causes inhibition of the hypothalamus to stop production