1 - Development of the Head, Mouth, and Pharynx Flashcards
Development of head involves:
-connective tissue and skeletal muscle structures that are of neural crest origin
Head region of embryo is associated with developing:
-nervous system
-digestive system
-respiratory system
Key distinguishing feature of head development is:
-formation of pharyngeal arches
Pharyngeal arches:
-begin developing around 3rd week of gestation in domestic animals
*neural crest-derived cells migrate into head and neck regions=begin to AGGREGATE
-6 pairs (5th and 6th are rudimentary)
First pharyngeal arch:
-divided into maxillary and mandibular process
-immediately caudal to oro-pharyngeal membrane that now seals off the foregut
Development of the face:
-involves formation, fusion, patterning of facial primordia that surround stomodeal depression
Primordia form from:
-proliferation of neural crest-derived mesenchyme
Development of face involves:
-single fronto-nasal prominence
-paired nasomedial and nasolateral processes
-paired maxillary and paired mandibular prominences
Fronto-nasal prominence:
-form 2 pairs of ectodermal thickenings
>nasal and lens placodes
Lens placodes:
-form before nasal placodes
-positioned laterally
Maxillary prominences:
-grow in size and extend medially to fuse with nasomedial processes
>*results in formation of maxillary process, primary palate, tissue of upper lip
Maxillary process is the future:
-maxilla
Upper lip:
-influenced by form and amount of fusion of the prominences
Mandibular prominences:
-fuse forming the lower jaw
Cleft lip: clinical relevance
-when fusion of nasiomedial processes and maxillary prominences does not occur properly
>philtrum is not formed
-congenital malformation
-rare in domestic animals
Nasal-lacrimal groove:
-early stages of development
-separates maxillary from nasal prominences
Nasolacrimal duct:
-when the nasal-lacrimal groove extends towards developing eye
>floor of ectodermal groove will lose contact with surface
Nasal pits:
-deepen and form sacs
-initially L and R nasal sacs are separated by a septum
Nasal sacs:
-separated from oral cavity by oro-nasal membrane which forms the primary palate
Maxillary process:
-common nasal cavity forms at caudal end of nasal sacs
-caudal plate atrophies
*leaves the maxillary process
Choana:
-opening
>direct communication between caudal portion of nasal cavity and oral cavity
Palatine processes:
-begin to grow from lateral walls of nasal cavity
Developing tongue:
-can initially fill the oral cavity and push into nasal cavity
Secondary palate:
-with growth of oral cavity there will be expansion of the palatine processes and fusion at midline
*partition
Where palate is fusing with maxillary process:
-small spaces in the palate remain
>incisive foramina
Incisive foramina:
-lead to incisive ducts
-allow small amounts of fluid from oral cavity to paired vomeronasal organ and to olfactory epithelium of nasal cavity
Conchae:
-projections of laminae that arise from lateral walls of nasal cavity
-made of mesoderm core and covered by ectodermal lining
>then became ossified
Turbinate bones:
-bony projections resemble scrolls
Meatus:
-divides the nasal cavity into 3 passages