1) Cardiopulm Physiology Flashcards
Goals of CPPT?
- Prevent
- Mitigate
- Reverse CP dysfxn
What can any insult to the O2 transport system cause?
Impairments & decr exercise tol
What can abn’s of CV & pulm systems cause?
Limitations in physical fxning
Minute Ventilation
Movement of air in & out of the lungs as a result of respiratory muscle activity
Normal minute ventilation?
21%
Where does gas exchange occur?
Between alveoli & blood in pulmonary capillaries
Where must blood have sufficient transit time to allow for diffusion?
Pulmonary Capillary
On which side of the heart does oxygenated blood enter?
Left side
During what phase of the cardiac cycle does blood enter the heart?
Diastole
When blood enters the L ventricle, what is the myocardium up to?
Its relaxed & compliant
W/what conditions is myocardial compliance low?
MI & LVH
What does decr myocardial compliance cause?
- Impaired ability to fill L ventricle
- Decr CO
- Dyspnea
What will factors that alter the oxyhemoglobin dissociation curve affect?
O2 delivery to skeletal muscle
What happens w/a shift to the left of the oxyhemoglobin dissociation curve?
Impairs the amount of O2 extracted by muscle
What happens w/a shift to the right of the oxyhemoglobin dissociation curve & why?
Acidosis & incr body temp bc it facilitates O2 unloading from hemoglobin
Steps of O2 transport pathway
1) Fully O2-ed blood gets delivered to peripheral tissues
2) Cells uptake O2 from blood
3) Cells use O2
4) Partially desaturated blood is returned to the lungs
If a pt can’t generate (-) pressure, what might need to happen?
Night time ventilation
During inspiration, is alveolar or thoracic pressure greater & why?
Alveolar–>Bc of respiratory muscle contraction