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Pharmacology > 1-50 > Flashcards

1-50 Flashcards

1
Q

Pharmacodynamics is

A

The part of pharmacology, which
deals with what a drug does to the
body

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2
Q

Which of the following types of drugs binds
to a receptor and produce an effect similar to
that of endogenous ligands?

A

Agonist

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3
Q

Drugs ‘x’ binds to drug ‘y’ as a result of which an inactive complex is formed. This
type of antagonism is called

A

Neutralizing antagonism

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4
Q

Epinephrine and acetylcholine act on the sympathatetic and parasympathetic autonomic nervous system, respsectively, and their effects are opposite to each other. This type of antagonism is called

A

Physiologic antagonism

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5
Q

Which of the following is not true about
competitive antagonism?

A

It is reversible

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6
Q

The relative measure f the safety and effectiveness of a drug is the ratio of TD50 to ED50. The pharmacological term used to
indicate this ratio is known as

A

Therapeutic index

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7
Q

A physician may prescribed carbidopa along with levodopa to increase the halflife levodopa and the duration of its antiparkinsonian effect. This way of enhancing of drug effect is known as

A

Potentiation

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8
Q

Which of the following is the main organ of
metabolism?

A

Liver

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9
Q

Chloramphenicol is known for which of the
following adverse side-effects?

A

Gray baby syndrome

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10
Q

Co-amoxiclav: amoxicillin/clavulanic acid :
co-trimoxazole _____

A

Trimethoprim/sulfamethoxazole

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11
Q

Which of the following drugs does not belong to the group?

I. Omeprazole
II. Lansoprazole
III. Aripiprazole
IV. Ranitidine

A

Aripiprazole

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12
Q

Which of the following anti-TB drugs can
cause red-green color blindness

I. Rifamcin
II. Isoniazid
III. Ethambutol
IV. Streptomycin

A

Ethambutol

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13
Q

Which of the following drugs is the least
considered as prodrug?

I. Captopril
II. Enalapril
III. Ramipril
IV. Accupril
V. None of the choices

A

Captopril

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14
Q

(Enervon®) tablet contains the following
EXCEPT:

I. Nicotinamide
II. Calcium
III. Ascorbic acid
IV. Magnesium

A

Magnesium

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15
Q

The sympathetic division of the ANS
stems from_____

A

Thoracolumbar

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16
Q

Which of the following prevents the storage of the acetylcholine to terminal vesicles?

I. Vesamicol
II. Reserpine
III. Botulinum toxin
IV. Hemicholinium

A

Vesamicol

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17
Q

The following are phase II reactions EXCEPT:

I. Acetylation
II. Methylation
III. Hydrolysis
IV. Sulfonation

A

Hydrolysis

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18
Q

Monoamine oxidase is an

A

Enzyme

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19
Q

Gon went to his farm to spray pesticide on his crops. Hour later he started to experience diarrhea, vomiting, bronchoconstriction and tachycardia. He was immediately sent to the hospital for treatment. Which of drugs should be given to Gon?

A

Atropine

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20
Q

Aside from the answer in #19, what other
drug can be given to Gon?

A

DAM

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21
Q

Cookie was diagnosed to have HPN and was prescribed beta-blockers for her treatment. She has a history of asthma. Which of the ff. beta-blockers should be given to cookie?

I. Propanolol
II. Timolol
III. Metoprolol

A

Metoprolol

22
Q

Andrea is going perform in the 2011 spring music festival. Hours before her performance she started to experience “stage fright”. Which of the ff. drugs can be given to manage her condition?

I. Lasartan
II. Enalapril
III. Propanolol
IV. Prazosin
V. Paracetamol

A

Propanolol

23
Q

The hydraulic equation is

A

BP=CO x PVR

24
Q

Which of the ff. are substrates of kininase II/peptidyl dipeptidase?

I. Angiotensin I
II. Bradykinin
III. Angiotensin II
IV. Angiotensin I and Bradykinin
V. Angiotensin I & Angiotensin II

A

Angiotensin I and Bradykinin

25
Q

Lanoxin acts on which of the following

I. Na/K ATPase pump
II. Na/H ATPase pump
III. H/K ATPase pump
IV. Na/Ca ATPase pump

A

Na/K ATPase pump

26
Q

Anti-arrhythmic drugs under class 4 acts
on

A

Ca channels

27
Q

Which of the following are loop diuretics?
I. Ethacrynic acid
II. Furosemide
III. Bumetimide
IV. Indapamide

A

I and IV (Ethacrynic acid and Indapamide)

28
Q

Andrei works as a pilot in an airline company. Which of the following antihistamines can he take?

I. Fexofenadine
II. Bromoheniramine
III. Promethazine
IV. Chlorpheniramine

A

Fexofenadine

29
Q

5HT3 antagonist are used for:

A

Nausea and vomiting

30
Q

Montelukast is a/an

A

Leukotriene pathway inhibitor

31
Q

DOC for typical absence seizure

A

Ethosuximide

32
Q

Flumazenil is

A

Benzodiazepine antagonist

33
Q

Arrange the correct order of the stages of anesthesia

I. Stage of excitement
II. Stage of medullary depression
III. Stage of surgical anesthesia
IV. Stage of analgesia

A

IV. Analgesia
I. Excitement
III. Surgical anesthesia
II. Medullary depression

34
Q

Dissociative anesthetic state characterized by catatonia, amnesia, and analgesia can be
produced by which drug?

A

Ketamine

35
Q

Neuroleptanesthesia is produce by which
drug combination?

A

Fentanyl, droperidol, and NO

36
Q

Which of the following does not belong to the group?

I. Lidocaine
II. Mepivacaine
III. Prilocaine
IV. Benzocaine
V. Arecholine

A

Benzocaine

37
Q

What is the treatment for malignant
hyperthermia?

A

Dantrolene

38
Q

Which of the following antiviral drug can
be used for Parkinsonism?

A

Amantadine

39
Q

Jet a five year old boy is having a problem with bed wetting. What drug can be prescribed for his condition?

A

Amitriptyline

40
Q

It is the dextrorotatory stereoisomer of
methylated derivative of levorphanol which is
used as antitussive?

A

Dextromethorphan

41
Q

HMG-CoA reductase inhibitors are advised to be given during night time with the EXEPTION of _______ which can be given anytime of the day.

A

Atorvastatin

42
Q

Which of the ff. vitamin can be used to
lower cholesterol levels?

A

Niacin

43
Q

Which of the given is considered the DMAD”s of 1st choice to treat rheumatoid arthritis?

A

Methotrexate

44
Q

Isoniazid can cause the following
laboratory data except?

A

Anemia

45
Q

DOC for chronic gout

A

Allopurinol

46
Q

A peptide hormone secreted by the posterior pituitary that participates in labor and delivery and elicits milk injection in lactating women.

A

Oxcytocin

47
Q

Which of the following beta-blockers is most widely used in the therapy of thyrotoxicosis?

A

Propranolol

48
Q

Marie is pregnant and was diagnosed with thyrotoxicosis. Which of the following thionamodes shoul be given to her?

A

PTU

49
Q

Soluble “peakles”, ultra long acting analog

A

Glargine

50
Q

Safest sulfonylurea for the elderly diabetics

A

Tolbutamide

Pharmacology (6 decks)

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