1-50 Flashcards
Pharmacodynamics is
The part of pharmacology, which
deals with what a drug does to the
body
Which of the following types of drugs binds
to a receptor and produce an effect similar to
that of endogenous ligands?
Agonist
Drugs ‘x’ binds to drug ‘y’ as a result of which an inactive complex is formed. This
type of antagonism is called
Neutralizing antagonism
Epinephrine and acetylcholine act on the sympathatetic and parasympathetic autonomic nervous system, respsectively, and their effects are opposite to each other. This type of antagonism is called
Physiologic antagonism
Which of the following is not true about
competitive antagonism?
It is reversible
The relative measure f the safety and effectiveness of a drug is the ratio of TD50 to ED50. The pharmacological term used to
indicate this ratio is known as
Therapeutic index
A physician may prescribed carbidopa along with levodopa to increase the halflife levodopa and the duration of its antiparkinsonian effect. This way of enhancing of drug effect is known as
Potentiation
Which of the following is the main organ of
metabolism?
Liver
Chloramphenicol is known for which of the
following adverse side-effects?
Gray baby syndrome
Co-amoxiclav: amoxicillin/clavulanic acid :
co-trimoxazole _____
Trimethoprim/sulfamethoxazole
Which of the following drugs does not belong to the group?
I. Omeprazole
II. Lansoprazole
III. Aripiprazole
IV. Ranitidine
Aripiprazole
Which of the following anti-TB drugs can
cause red-green color blindness
I. Rifamcin
II. Isoniazid
III. Ethambutol
IV. Streptomycin
Ethambutol
Which of the following drugs is the least
considered as prodrug?
I. Captopril
II. Enalapril
III. Ramipril
IV. Accupril
V. None of the choices
Captopril
(Enervon®) tablet contains the following
EXCEPT:
I. Nicotinamide
II. Calcium
III. Ascorbic acid
IV. Magnesium
Magnesium
The sympathetic division of the ANS
stems from_____
Thoracolumbar
Which of the following prevents the storage of the acetylcholine to terminal vesicles?
I. Vesamicol
II. Reserpine
III. Botulinum toxin
IV. Hemicholinium
Vesamicol
The following are phase II reactions EXCEPT:
I. Acetylation
II. Methylation
III. Hydrolysis
IV. Sulfonation
Hydrolysis
Monoamine oxidase is an
Enzyme
Gon went to his farm to spray pesticide on his crops. Hour later he started to experience diarrhea, vomiting, bronchoconstriction and tachycardia. He was immediately sent to the hospital for treatment. Which of drugs should be given to Gon?
Atropine
Aside from the answer in #19, what other
drug can be given to Gon?
DAM
Cookie was diagnosed to have HPN and was prescribed beta-blockers for her treatment. She has a history of asthma. Which of the ff. beta-blockers should be given to cookie?
I. Propanolol
II. Timolol
III. Metoprolol
Metoprolol
Andrea is going perform in the 2011 spring music festival. Hours before her performance she started to experience “stage fright”. Which of the ff. drugs can be given to manage her condition?
I. Lasartan
II. Enalapril
III. Propanolol
IV. Prazosin
V. Paracetamol
Propanolol
The hydraulic equation is
BP=CO x PVR
Which of the ff. are substrates of kininase II/peptidyl dipeptidase?
I. Angiotensin I
II. Bradykinin
III. Angiotensin II
IV. Angiotensin I and Bradykinin
V. Angiotensin I & Angiotensin II
Angiotensin I and Bradykinin
Lanoxin acts on which of the following
I. Na/K ATPase pump
II. Na/H ATPase pump
III. H/K ATPase pump
IV. Na/Ca ATPase pump
Na/K ATPase pump
Anti-arrhythmic drugs under class 4 acts
on
Ca channels
Which of the following are loop diuretics?
I. Ethacrynic acid
II. Furosemide
III. Bumetimide
IV. Indapamide
I and IV (Ethacrynic acid and Indapamide)
Andrei works as a pilot in an airline company. Which of the following antihistamines can he take?
I. Fexofenadine
II. Bromoheniramine
III. Promethazine
IV. Chlorpheniramine
Fexofenadine
5HT3 antagonist are used for:
Nausea and vomiting
Montelukast is a/an
Leukotriene pathway inhibitor
DOC for typical absence seizure
Ethosuximide
Flumazenil is
Benzodiazepine antagonist
Arrange the correct order of the stages of anesthesia
I. Stage of excitement
II. Stage of medullary depression
III. Stage of surgical anesthesia
IV. Stage of analgesia
IV. Analgesia
I. Excitement
III. Surgical anesthesia
II. Medullary depression
Dissociative anesthetic state characterized by catatonia, amnesia, and analgesia can be
produced by which drug?
Ketamine
Neuroleptanesthesia is produce by which
drug combination?
Fentanyl, droperidol, and NO
Which of the following does not belong to the group?
I. Lidocaine
II. Mepivacaine
III. Prilocaine
IV. Benzocaine
V. Arecholine
Benzocaine
What is the treatment for malignant
hyperthermia?
Dantrolene
Which of the following antiviral drug can
be used for Parkinsonism?
Amantadine
Jet a five year old boy is having a problem with bed wetting. What drug can be prescribed for his condition?
Amitriptyline
It is the dextrorotatory stereoisomer of
methylated derivative of levorphanol which is
used as antitussive?
Dextromethorphan
HMG-CoA reductase inhibitors are advised to be given during night time with the EXEPTION of _______ which can be given anytime of the day.
Atorvastatin
Which of the ff. vitamin can be used to
lower cholesterol levels?
Niacin
Which of the given is considered the DMAD”s of 1st choice to treat rheumatoid arthritis?
Methotrexate
Isoniazid can cause the following
laboratory data except?
Anemia
DOC for chronic gout
Allopurinol
A peptide hormone secreted by the posterior pituitary that participates in labor and delivery and elicits milk injection in lactating women.
Oxcytocin
Which of the following beta-blockers is most widely used in the therapy of thyrotoxicosis?
Propranolol
Marie is pregnant and was diagnosed with thyrotoxicosis. Which of the following thionamodes shoul be given to her?
PTU
Soluble “peakles”, ultra long acting analog
Glargine
Safest sulfonylurea for the elderly diabetics
Tolbutamide
