08: Proteins

Question 1

1. Where are the major sites of protein synthesis?

Answer 1

1. liver and immune system

Question 2

(affect of age on protein levels)

1. young?
2. old?

Answer 2

1. globulins and albumins low (high globulins after colostrum though)
2. high immunoglobins and low albumin

Question 3

1. What protein type contributes to 75% of plasma osmotic activity?

Answer 3

1. albumin

Question 4

(hypoproteinemia)

1. selective hypoproteinemia = ?

2-6. five causes

Answer 4

1. isolated hypoalbuminemia
2. liver failure (dec production)
3. selective glomerular loss
4. nutritional (must be severe)
5. non-selective loss with ^globulin production
6. inflammation (albumin is neg APP, globulin is POS)

Question 5

(Generalized of panhypoproteinemia)

1. usually due to what?
2. also due to what?

Answer 5

1. ^non-selective losses (hemorrhage, third space, burns, GI)
2. dilutional

Question 6

(hyperproteinemia)

1. increased albumin = ?
2. increased globulins = ?

Answer 6

1. dehydration
2. post-colostrum

^prod (inflamm - polyclonal, neoplastic - monoclonal)