07 pregnanacy Flashcards

1
Q

Species with CL as sole source of progesterone

A
Pig
Goat
Llama 
Cat
Dog
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2
Q

Species with CL and placental production of progesterone

A

Horse
Sheep
Cow

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3
Q

Maternal recognition of pregnancy

A

Luteolysis must be prevented
embryonic secretion of substances
contact with uterine epithelium

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4
Q

Ruminants- Maternal recognition of preg

A

trophoblast cells of conceptus produces INF-t between day 10-21
binds to endometrium and block synthesis of oxytocin receptors therefore oxytocin cant bind and does not stimulate endometrial production of PGF2a

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5
Q

Sow- Maternal recognition of preg

A

conceptus produces estradiol on day 13-15

estrogen causes rerouting of endometrial PGF2a into lumen of uterus and not in general circulation

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6
Q

Mare- Maternal recognition of preg

A

Conceptus must migrate around uterus!

signal not well defined

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7
Q

Dog- Maternal recognition of preg

A

None

CL maintained whether animal is pregnant or not

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8
Q

Cat- Maternal recognition of preg

A

Fetoplacental relaxin stimulates prolactin which is luteotropic and helps support CL

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9
Q

Roles of Placenta

A
nutrient exchange
gas exchange
stores waste
protective 
endocrine organ
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10
Q

Distribution of Contact Areas

A
Diffuse- distributed evenly through sac
horse and pig
Cotyledonary- certain points of contact- maternal caruncle+fetal cotyledon=placentome
ewe, cow
Zonary- zone of contact
dog, cat 
Discoid- contact in 1-2 round areas
man, monkey, rodent
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11
Q

Degree of Invasion

A
Epitheliochorial
5-6 layers
least invasive
mare, sow, cow, sheep goat
Endotheliochorial
4-5 layers
carnivores
Hemochorial
3 layers
primates and rodents
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12
Q

Interdigitation of Vasculature

A
Simple--> Complex
Folded-pig
Lamellar- horses
Trabecular- human
Villous- cow
Labyrinth- dog
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13
Q

Degree of Maternal tissue loss

A

Adeciduate- non-invasive, complete seperation of maternal and fetal tissues. Sow, mare and ruminant
Deciduate- invasive, loss of maternal tissue at parturition. Carnivores, humans, rodents

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14
Q

Horse-placenta type

A

diffuse
epitheliochorial
microcotyledonary
adeciduate

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15
Q

Llama- placenta type

A

diffuse
epitheliochorial
villous
Adeciduate

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16
Q

Pig–placenta type

A

diffuse
epitheliochorial
folded
adeciduate

17
Q

Cow–placenta type

A

Cotyledonary
Epitheliochorial
Villous
Adeciduate

18
Q

Ewe–placenta type

A

Cotyledonary
Epitheliochorial
Villous
Adeciduate

19
Q

Goat–placenta type

A

Cotyledonary
Epitheliochorial
Adeciduate

20
Q

Dog–placenta type

A

Zonary
Endotheliochorial
Labyrinth
Deciduate

21
Q

Cat-placenta type

A

Zonary
Endotheliochorial
Labyrinth
Deciduate

22
Q

Primate-placenta type

A

Discoidal
Hemochorial
Trabecullar
Deciduate

23
Q

Mouse-placenta type

A

Discoidal
Hemochorial
Labyrinth
Deciduate

24
Q

Ferguson Reflex

A

Uterine contraction–> cervical stretch–> afferent impulses from cervical stretch receptors–>reflex oxytocin secretion

25
Q

In human when woman is at risk for premature labor, give ____

A

Gluccocorticoid to accelerate fetal lung development

26
Q

In placenta

A

fetus releases cortisol which increases biosynthesis therefore decreasing progesterone

27
Q

Hypothalamus Pituitary Adrenal Axis

A

hypothalamus releases CRH which signals to AP to release ACTH which causes adrenal cortex to release cortisol