06 - spinal cord disorders Flashcards
anomalies are usually recognized when?
when the animal starts to walk
what age dogs tend to get immune mediated disorders?
commoonly what breed?
young ones
boxers
couple of toxins that affect spinal cord?
strychnine and tetanus
what is hyperpathia?
exaggerated resposne to a painful stimulus
propriocetpive deficits and ataxia occur early in spinal cord disease
(paresis (weakness) can result from injury to UMN or LMN tracts)
- UMN injury causes weakness where?
- LMN injury causes weakness where?
- UMN injury causes increased extensor muscle tone when recumbent
- LMN injury causes decreased spinal reflexes, decreased muscle tone, and muscle atorphy
- in limbs caudal to lesion
- in limbs at the level of the injury
(nociceptive (pain) loss)
- injury to ascending nociceptive tracts in the spinal cord results in what?
- lack of deep pain indicates what?
- depressed or absent pain from stimuli caudal to the injury
- severe spinal cord injury
- intramedullary lesions cause what kinds of Cx?
- extramedullary lesions cause what kinds of Cx?
- symmetrical Cx
- asymmetrical signs (ipsilateral to lesion)
(imaging)
What is the test of choice for diagnosing inflammatory spinal cord disease?
CSF analysis
(medical tx)
- degenerative disorders causing compression of the spinal cord treated with what?
- spinal cord trauma should be treated immediately after injury with what?
- glucocorticoids at antiinflammatory doses
- large doses of corticosteroids
- infections should be treated with what?
- discospondylitis is usually caused by what bacteria?
- abx that cross BBB
- staph
immune mediated disorders are treated with what?
prednisone (immunosuppression)
neoplasia is hard to treat cause most chemo agents don’t cross BBB
what drug does?
lomustine