Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FM3_ EB > Zoonotic infections > Flashcards

Zoonotic infections Flashcards

1
Q

What organism is the cause of cat scratch disease

A

Bartonella henselae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the morphology of bartonella henselae

A

slightly curved gram - rods

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe the presentation of cat scratch disease

A

papules and pustiles around a scratch or bite

non-healing wound

lynphadenopathy proximal to wound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is Parindaud’s oculoglandular syndrome

A

ocular granuloma or conjunctivitis and preauricular
LN’opathy; following inoculation of B. henselae into the conjunctiva

seen in kids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Children are more likely to develop complications of B hensalae infection including:

A

fevers of unknown origin
Parinaud’s oculoglandular syndrome
encephalitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In addition to CSD, what other syndromes may develop from bartonella hensaleae infection?

A 
bacillary angiomatosis
peliosis hepatis
endocarditis
osteomyelitis
uveitis
persistent fever
breast abscess
neurologic manifestations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

_____ may transmit bartonella between cats

A

fleas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What drug may be effective in accelerating recovery from symptomatic signs of bartonella infection

A

azithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can bartonella infection be prevented in humans

A 
avoid rough play with kittens
wash bites/ scratches
flea control
immunocompromised people adopt only seronegative adult cats
vaccination of cats
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the morphology of yersinia pestis

A

gram negative bipolar rod

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Where in the US is plague most commonly seen

A

Colorado, New Mexico, Arizona, California, Nevada

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How is yersinia pestis transmitted?

A

fleas to rodents to small carnivores

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

List the three clinical forms of plague

A
  1. bubonic: acute febrile lymphadenitis, may see meningitis
  2. septicemic: hematogenous spread, leading to shock/ DIC
  3. Pneumonic: inhalation as route of infection or hematogenous spread, extremely fatal form
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Yersinia pestis can easily be mistaken for a ______ on culture/ stain

A

diplococcus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What antibiotics are used to treat infection with Yersinia pestis?

A
  • streptomycin/ gentamici
  • tetracyclines/ fluoroqinolones/ chloramphenicol if there is meningitis, pleuritis, myocarditis
  • levlofloxacin

susceptible to penicillin and ampicillin in vitro but not in vivo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Is there a vaccine for plague?

A

Yes, for high risk workers and travelers
Formalin inactivated
Also a vaccination for cats but not part of core feline vaccination regimen

17
Q

What is the morphology of tularemia?

A

Gram negative bipolar rod (not diplococcus)

18
Q

How is tularemia transmitted?

A

Rabbits and other small mammals-
undercooked game meat
waterborne
ticks and other arthropods

19
Q

List clinical forms of tularemia in humans

A 
ulceroglandular
oculoglandular 
exudative pharyngeal form
systemic typhoidal form
pneumonic form
20
Q

How is tularemia treated?

A

streptomycin, ciprofloxacin, or doxycycline

21
Q

______ is a spirochete with over 250 serovars

A

leptospira interrogans

22
Q

Leptospires can persist in the ____ of animals without causing disease leading to prolonged shedding

A

renal tubules

23
Q

____ are the most common source of leptospira infection in humans

A

rats

others: dogs, livestock, rodents

24
Q

How does human infection with leptospira most commonly occur?

A

contact with infected water- rice field fever etc

25
Q

List clinical forms of leptospirosis

A
  1. “Weil’s disease” is the
    name for the classic hepatic and renal form of disease. After an incubation period of 7-12
    days, patients develop fever (biphasic), headache, and “flu-like” illness followed
    within a few days by hepatomegaly, jaundice, and renal insufficiency.
  2. The less severe, anicteric disease also presents as an initial flu-like illness, but this can be
    followed by a second phase of intense headaches, severe myalgia, abdominal pain, and nausea, and sometimes rash, conjunctivitis/uveitis, and conjunctival hemorrhage, aseptic meningitis that is IMMUNE MEDIATED
26
Q

What was unique about the leptospirosis outbreak known as mystery diseas

A

caused pulmonary hemorrhage with high mortality

27
Q

_______ is a small Gram (-) coccobacillus; facultative intracellular pathogen; survives and replicates in
leukocytes

A

Brucella

28
Q

What is the major virulence factor of Brucella

A

LPS

29
Q

How can Brucella be transmitted?

A

unpasturized dairy

contact with tissues from infected cattle

30
Q

What is the clinical presentation of Brucellosis?

A

undulating fever, night sweats, headaches, chills, weakness, arthralgia/myalgia, reproductive tract issues

31
Q

How can brucellosis be treated

A

doxycycline + rifampin

use TMP/SMX in kids to avoid dental staining

32
Q

How should people who accidentally vaccinate themselves with the RB51 brucella vaccine be treated?

A

3 weeks of doxycycline + rifampin

FM3_ EB (25 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions