Zaidi: Specialized Tissues, Stem Cells and Tissue Renewal II

Question 1

Sensory epithelia is derived from

Answer 1

Ectoderm

Question 2

One olfactory receptor can bind how many classes of odorant molecules– they work via what mechanism

Answer 2

Only one

G-protein coupled receptor- adenylate cyclase-cAMP

Question 3

What differentiates into olfactory neurons

Answer 3

Basal stem cells in contact with the basal lamina

Question 4

Odorant receptor protein function with axonal guidance

Answer 4

Odorant receptor proteins assist in axonal guidance and allow growth cone to migrate to and establish connection with correct glomerulus in olfactory bulb

Question 5

Olfactory receptor cell regeneration

Answer 5

On of the few instances of adult neurogenesis in the CNS

Question 6

Stem cells are prevalent in what area of brain

Answer 6

Ventricles of forebrain

Hippocampus

Question 7

Stem cells in ventricles migrate to

Answer 7

Olfactory bulb

Question 8

Stem cells of hippocampus

Answer 8

Involved in learning and memory formation

Continuous turnover of cells in hippocampus

Question 9

Neurospheres

Answer 9

Clusters of neural stem cells, neural cells and glial cells

Can stay as stem cells, differentiate into neurons or both neurons and glial cells

Question 10

What activates quiescent stem cell proliferation

Answer 10

Neuronal activity (learning)
Induction of long-term potentiation
In vitro depolarization
Electrical stimulation

Question 11

Neoblasts

Answer 11

Undifferentiated cells, make up 20% of cells in body