zafirlukast Flashcards

1
Q

what is the classification of zafirlukast

A

leukotriene receptor antagonists (antiasthmatic)

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2
Q

what is the trade name for zafirlukast

A

Accolate

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3
Q

what is the pharmacotherapeutic (use) for zafirlukast

A

prophylaxis or treatment of chronic asthma (long-term drug)

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4
Q

how is zafirlukast administered

A

orally

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5
Q

what is the pharmacodynamics of zafirlukast

A

blocks receptors for the leukotrienes bound to the amino acid cysteine

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6
Q

what are the C/I and precautions of zafirlukast

A

hypersensitivity

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7
Q

what are the A/E of zafirlukast

A

HA, gastritis/diarrhea, pharyngitis, and rhinitis

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8
Q

what are the D/I of zafirlukast

A

theophylline, warfarin, aspirin, erthromycin

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9
Q

what health status would you asses for pts taking zafirlukast

A

assess medical status and liver function

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10
Q

what life span and gender would you asses for pts taking zafirlukast

A

pregnancy category B

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11
Q

what life style, diet, and habit would you asses for pts taking zafirlukast

A

take medication on empty stomach. if pt experiences diarrhea, encourage water intake

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12
Q

what environment would you asses for pts taking zafirlukast

A

generally given at home

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13
Q

how would you maximize the therapeutic effects of zafirlukast

A
  • ensure that the pt takes zafirlukast twice daily despite the absence of symptoms
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14
Q

how would you minimize the A/E of zafirlukast

A

ensure that the pt takes the medication only as prescribed

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15
Q

what are the patient and family education of zafirlukast

A
  • explain that zafirlukast is used in maintenance therapy
  • encourage pts to take nonnarcotic analgesics if HA occurs
  • if diarrhea occurs, replenish lost fluids. encourage water
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16
Q

what are the ongoing assessment and evaluation of zafirlukast

A

assess whether the pt needs beta-agonist drugs in addition to zafirlukast