Yellow Fever

Question 1

What transmits Yellow Fever?

Answer 1

Aedes

Question 2

Where is yellow fever found?

Answer 2

Endemic in central and South America plus tropical Africa

Question 3

What are the features of yellow fever?

Answer 3

Asymptomatic 
Flu like
Then some progress to toxic phase
- fever
- renal and liver failure
- GI bleed

Question 4

How do you diagnose yellow fever?

Answer 4

Clinical
PCR
IgM
Councilman bodies in liver histology

Question 5

How do you prevent yellow fever?

Answer 5

Vaccinate- one dose
YF vaccination certificate
Vector control and surveillance
Outbreak surveillance: one case = outbreak

Question 6

What are the contraindications for the yellow fever vaccination?

Answer 6

Severe egg allergy
Severe Immunosuppression
Under 9mnth
Pregnancy (usually)

In over 60s, have to weight up risk vs benefit

Question 7

What are the Eliminate Yellow Fever Epidemics objectives?

Answer 7

Protect at risk populations
Prevent international spread
Contain outbreaks rapidly

Question 8

What are the EYEs competencies of success?

Answer 8

Affordable vaccines
Political commitment at all levels
High level governance with long term partnership
Synergies with other health programmes
Research and development for better tools and practices

Question 9

What steps round you take to control a yellow fever outbreak?

Answer 9

Notify WHO of any confirmed cases
Mass immunisation (>80%)
Vector control can consider widespread spraying in large urban outbreak
Collect specimens for lab confirmation of any suspected cases