Yellow fever

Question 1

List the 2 cycles of the yellow fever

Answer 1

1.Jungle cycle
animal to mosquitos transmission

2. Urban cycle
   * Mosquitos to human transmission

Question 2

Pathogenesis of yellow fever

Answer 2

.After infection the virus first replicates locally, followed by transportation to the rest of the body via the lymphatic system.[1]
Following systemic lymphatic infection, the virus proceeds to establish itself throughout organ systems, including the heart, kidneys, adrenal glands, and the parenchyma of the liver; high viral loads are also present in the blood.
Necrotic masses (Councilman bodies) appear in the cytoplasm of hepatocytes.

Question 3

clinical features of yellow fever

Answer 3

• After an extrinsic incubation period (8-10 days )
• fever ,chills ,myalgia ,headache
• hemorrhage manifestations
• hepartitis
• renal failure
• platelet dysfunction