Adenoviruses Flashcards
1
Q
How is the adenovirus transmitted?
A
Usually enters the host by inhalation of the droplets nuclei or by oral route
Direct inoculation of the nasal, conjunctiva mucosa by hands and contaminated towels
2
Q
Discuss the pathogenesis of the adenovirus
A
The virus replicates in the epithelial cells and initiates necrosis and inflammation
Viraemia sometimes occurs and spreads to distant sites eg kidneys
3
Q
What are the clinical manifestations of adenovirus
A
Larg % of the population is asymptomatic with most presenting with features of UTI, respiratory diseases, eye infection, and gut infection
4
Q
How is the Adenovirus diagnosed?
A
PCR, Respiratory samples ( swabs or aspirates)
5
Q
How is adenovirus treated?
A
there is no specific treatment (vaccines are only given to the military
