varicella zoster virus hhv-3

Question 1

Properties of varicella-zoster virus

Answer 1

• chicken pox

* highly contagious

Question 2

Pathogenesis of varicella-zoster virus

Answer 2

*MOT through respiratory droplets

Primary infection in the mucosa of the respiratory tract and spreads through the bloodstream and lymphatic system . Then spreads throughout the body and skin

Question 3

Clinical manifestations of the varicella-zoster virus

Answer 3

> Chicken pox: vesicular rash and fever, lymphadenopathy
*Latency in dorsal root, reactivation causes virion transport down sensory nerve

> Severe complications
*viral pneumonia, encephalitis, and hemorrhagic chickenpox

Question 4

How is the HHV 3 diagnosed

Answer 4

*Clinically, PCR, Serology, IgG will show past infections and IgM will show recent infection

Question 5

How is the HHV 3 treated

Answer 5

*Acyclovir accelerates resolution, valacyclovir, and famciclovir