Wound Management Flashcards
Avulsion
- Tearing away of body tissue due to shear
- Degloving injury
- Flaps of tissue
- Avulsed part may be attached by flap of skin
What is the golden period in regards to timing of injury?
- Within 6 hours of injury - this is when bacterial numbers are still low
- Beyond 6 hours of injury, bacterial growth reach numbers that risk infection (105 per gram of tissue)
- The earlier you can get to a wound, the better you can close it off without it becoming infected
Degree of Contamination: clean, clean contaminated, contaminated, dirty/infected
- Clean: surgically created, no hollow viscous opened
- Clean contaminated: minimal contamination; contamination can be effectively removed; includes surgery of hollow viscus (intestines, stomach, etc)
- Contaminated: open traumatic wounds; break in aseptic technique
- Dirty/infected: Old traumatic wounds; perforated viscus; clinical infection (open abdomen where there is already peritonitis)
Will the presence of bacteria alone cause an infection in a wound?
No, you need more than just some bacteria on a wound to cause an infection. Usually there is some compromised effect of local immunity, it depends on the blodo supply and the amoutn of traumatized tissue, and the amoutn/type of foreign debris present. Patient age also plays a role.
When to culture and what to culture
- When to culture:
- BEFORE anitbiotics if possible
- When there is gross evidence of infection - not useful to culture a fresh wound
- What to culture
- Deep tissue layer, NOT the surface
Acute Wound Management Goals
- Remove obvious devitalized tissue
- Remove foreign bodies/debris
- Reduce bacterial numbers to as close to zero as possible
- Wound closure at earliest appropriate time
Acute Wound Treatment - Lavage
- Can remove up to 90% of bacteria
- Large quantities - moderate pressure
- 35 mL syringe + 18 g needle = 7-8 psi
- 1 L plastic bag within a 300 mmHg pressurized cuff
- Main thing - deliver 7-8 psi
- Contraindication in puncture wounds b/c fluid can’t get back out, and results in iatrogenic tissue edema!!
Most common lavage solution:
Normal saline
Two antiseptic lavage solutions:
- 0.05% Chlorhexidine
- any more will cause too much damage to fibroblasts in the wound
- 0.1% povidone-iodine
Pros and Cons of tap water with lavage:
- Pros
- GROSS contamination
- Cheap
- Available
- Ease of application
- Cons
- Hypotonic
- Cytotoxic trace elements
- Not antimicrobial
Pros and cons of using electrolyte solutions with lavages
- Pros:
- Isotonic
- Least cytotoxic
- Cons
- Not antimicrobial
pros and cons of using normal saline in lavage
- Pros - isotonic
- Cons
- More acidic than LRS
- Not antimicrobial
How to make 0.05% Chlorhexidine
- Stock (2%) added to sterile water - 1:40 dilution
- 25 mL per liter of sterile water
- DO NOT USE SALINE to mix - liquid will become foamy!
Pros and cons of using 0.05% chlorhexidine in lavage
- Pros
- Wide antimicrobial spectrum
- Residual activity - increases when repeated
- Minimally inactivated by organic matter
- Cons
- Slows granulation and contraction in some rat models
- Proteus, Pseudomonas, Candida resistance
- Corneal toxicity
How to make 0.1% povidone-iodine
- Stock (10%) added to sterile water, LRS, or saline … 1:100 dilution
- 10 mL per liter of water/LRS/saline